Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetraethylene Glycol SCHEMBL9177374 | 1.00 | THRB (0.41) | THRBALDH1A1TP53HIF1ACYP3A4 | |
| Triethylene Glycol SCHEMBL28384410 | 0.95 | THRB (0.43) | THRBALDH1A1TP53HIF1ACYP3A4 | |
| Triethylene Glycol SCHEMBL5375363 | 0.92 | ALDH1A1 (0.36) | THRBALDH1A1TP53HIF1ACYP3A4 | |
| Tetraethylene Glycol SCHEMBL11031088 | 0.92 | THRB (0.46) | THRBALDH1A1TP53HIF1ACYP3A4 | |
| Triethylene Glycol SCHEMBL671552 | 0.92 | MEN1 (0.38) | THRBALDH1A1MAPK1TSHRMEN1 | |
| Tetraethylene Glycol SCHEMBL9167033 | 0.92 | MEN1 (0.38) | THRBALDH1A1MAPK1TSHRMEN1 | |
| Tetraethylene Glycol SCHEMBL3293861 | 0.92 | MEN1 (0.38) | THRBALDH1A1MAPK1TSHRMEN1 | |
| Di(Hydroxyethyl)Ether SCHEMBL9555336 | 0.91 | TSHR (0.36) | THRBALDH1A1MAPK1TSHRMEN1 | |
| Di(Hydroxyethyl)Ether SCHEMBL27754623 | 0.91 | TSHR (0.36) | THRBALDH1A1MAPK1TSHRMEN1 | |
| Di(Hydroxyethyl)Ether SCHEMBL8961314 | 0.91 | THRB (0.44) | THRBALDH1A1TP53HIF1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871907-A2 | METHOD OF IMPARTING IMPACT RESISTANCE TO A PLASTIC OPHTHALMIC LENS, COMPOSITIONS FOR USE THEREIN AND A LENS PREPARED THEREBY | ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) | 1998-10-21 | — | — | EP | disclosed |
| WO-1996023243-A1 | METHOD OF IMPARTING IMPACT RESISTANCE TO A PLASTIC OPHTHALMIC LENS, COMPOSITIONS FOR USE THEREIN AND A LENS PREPARED THEREBY | ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) | 1996-08-01 | — | — | WO | disclosed |