Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 7/20 | 0.64 |
| ▸ | PDE4A | P27815 | 11/20 | 0.60 |
| ▸ | PDE4B | Q07343 | 11/20 | 0.60 |
| ▸ | PDE4C | Q08493 | 11/20 | 0.60 |
| ▸ | PDE4D | Q08499 | 11/20 | 0.60 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | CNOT7 | Q9UIV1 | 4/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8655611 | 0.91 | PDE4A (0.65) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL21381252 | 0.85 | ADORA2A (0.82) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8656014 | 0.83 | PDE4A (0.62) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8912388 | 0.82 | PDE4A (0.74) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9040437 | 0.82 | ADORA2A (0.67) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7451534 | 0.81 | ADORA2A (0.59) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL27515234 | 0.81 | ADORA2A (0.66) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8660416 | 0.80 | PDE4A (0.60) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL7455511 | 0.80 | ADORA2A (0.58) | ADORA2APDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8659000 | 0.79 | ADORA2B (0.59) | ADORA2APDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5728686-A | TREATMENT OF MUSCULAR DYSTROPHY | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-03-17 | — | — | US | disclosed |