Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 7/20 | 0.59 |
| ▸ | PDE4A | P27815 | 4/20 | 0.59 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.59 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.59 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.59 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.59 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22471417 | 0.86 | ADORA2B (0.68) | ADORA2BPDE4AADORA2APDE4BPDE4C | |
| SCHEMBL8656098 | 0.85 | ADORA2B (0.63) | ADORA2BPDE4AADORA2APDE4BPDE4C | |
| SCHEMBL8657814 | 0.82 | ADORA2B (0.49) | ADORA2BPDE4AADORA2APDE4BPDE4C | |
| SCHEMBL8660416 | 0.82 | PDE4A (0.60) | ADORA2BPDE4AADORA2APDE4BPDE4C | |
| SCHEMBL2119480 | 0.82 | ADORA2B (0.63) | ADORA2BPDE4AADORA2APDE4BPDE4C | |
| SCHEMBL460341 | 0.82 | ADORA2B (0.63) | ADORA2BPDE4AADORA2APDE4BPDE4C | |
| SCHEMBL8659911 | 0.80 | ADORA2B (0.64) | ADORA2BADORA2ALMNAMAPTACHE | |
| SCHEMBL27552726 | 0.80 | ADORA2B (0.60) | ADORA2BPDE4AADORA2APDE4BPDE4C | |
| SCHEMBL516014 | 0.79 | ADORA2B (0.72) | ADORA2BPDE4AADORA2APDE4BPDE4C | |
| SCHEMBL8660345 | 0.79 | ADORA2A (0.64) | ADORA2BPDE4AADORA2APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5728686-A | TREATMENT OF MUSCULAR DYSTROPHY | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-03-17 | — | — | US | disclosed |