Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.79 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.79 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.79 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Demeton S SCHEMBL117918 | 0.89 | ALDH1A1 (0.59) | ALDH1A1HSD17B10CYP3A4MEN1KMT2A | |
| Disulfoton SCHEMBL27180 | 0.89 | ALDH1A1 (1.00) | ALDH1A1HSD17B10CYP3A4MEN1KMT2A | |
| Disulfoton SCHEMBL6732289 | 0.89 | ALDH1A1 (1.00) | ALDH1A1HSD17B10CYP3A4MEN1KMT2A | |
| Demeton S SCHEMBL6732303 | 0.89 | ALDH1A1 (0.59) | ALDH1A1HSD17B10CYP3A4MEN1KMT2A | |
| Disulfoton SCHEMBL7610063 | 0.89 | ALDH1A1 (1.00) | ALDH1A1HSD17B10CYP3A4MEN1KMT2A | |
| Ethion SCHEMBL4108994 | 0.85 | ALDH1A1 (0.92) | ALDH1A1HSD17B10CYP3A4MEN1KMT2A | |
| Disulfoton SCHEMBL8932165 | 0.84 | ALDH1A1 (0.89) | ALDH1A1HSD17B10CYP3A4MEN1KMT2A | |
| Demeton S SCHEMBL20544186 | 0.82 | ALDH1A1 (0.52) | ALDH1A1HSD17B10CYP3A4MEN1KMT2A | |
| Demeton S SCHEMBL7254122 | 0.82 | ALDH1A1 (0.52) | ALDH1A1HSD17B10CYP3A4MEN1KMT2A | |
| Demeton S SCHEMBL117917 | 0.82 | MEN1 (0.72) | ALDH1A1HSD17B10CYP3A4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5817880-A | 2-FLUOROALKYL-4-HYDROXYCYCLOPENT-2-ENONE | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1998-10-06 | — | — | US | disclosed |