Disulfoton

Disulfoton

SCHEMBL6732289

CCOP(=S)(OCC)SCCSCC.CCOP(=S)(OCC)SCCSCC

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 1.00
HSD17B10 Q99714 3/20 1.00
CYP3A4 P08684 1/20 1.00
MEN1 O00255 4/20 0.53
KMT2A Q03164 4/20 0.53
TDP1 Q9NUW8 1/20 0.53
TSHR P16473 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Disulfoton SCHEMBL27180 1.00 ALDH1A1 (1.00) ALDH1A1HSD17B10CYP3A4MEN1KMT2A
Disulfoton SCHEMBL7610063 1.00 ALDH1A1 (1.00) ALDH1A1HSD17B10CYP3A4MEN1KMT2A
Ethion SCHEMBL4108994 0.96 ALDH1A1 (0.92) ALDH1A1HSD17B10CYP3A4MEN1KMT2A
Disulfoton SCHEMBL8932165 0.94 ALDH1A1 (0.89) ALDH1A1HSD17B10CYP3A4MEN1KMT2A
SCHEMBL29350865 0.90 ALDH1A1 (0.81) ALDH1A1HSD17B10CYP3A4MEN1KMT2A
Demeton S SCHEMBL8660394 0.89 ALDH1A1 (0.79) ALDH1A1HSD17B10CYP3A4MEN1KMT2A
SCHEMBL8535140 0.89 ALDH1A1 (0.78) ALDH1A1HSD17B10CYP3A4MEN1KMT2A
Disulfoton SCHEMBL8669947 0.88 ALDH1A1 (0.77) ALDH1A1HSD17B10CYP3A4MEN1KMT2A
SCHEMBL10109438 0.84 ALDH1A1 (0.71) ALDH1A1HSD17B10CYP3A4MEN1KMT2A
Disulfiram SCHEMBL16446141 0.82 ALDH1A1 (0.68) ALDH1A1HSD17B10CYP3A4MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6680065-B2 FOR TREATMENT OF WOODY PLANTS; EMPLOYED IN HOLLOW PREFORMED IN THE WOODY PLANT BAYER AKTIENGESELLSCHAFT (DE) 2004-01-20 US disclosed
US-6528079-B2 For treatment of woody plants; employed in a hollow preformed in the woody plant BAYER AKTIENGESELLSCHAFT (DE) 2003-03-04 US disclosed
US-20020061323-A1 SHAPED BODIES WHICH RELEASE AGROCHEMICAL ACTIVE SUBSTANCES BAYER AKTIENGESELLSCHAFT (DE) 2002-05-23 US disclosed
US-20010039248-A1 Shaped bodies which release agrochemical active substances PODSZUN WOLFGANG (DE) 2001-11-08 US disclosed
US-5925676-A INSECICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-07-20 US disclosed
WO-1997036471-A1 GELATIN-BASED COATINGS FOR PLANT SEEDS AND PROPAGULES MONSANTO COMPANY (US) 1997-10-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020061323-A1 SHAPED BODIES WHICH RELEASE AGROCHEMICAL ACTIVE SUBSTANCES AGL, CHMP4B, GUSB ALDH1A1 729/4885HSD17B10 548/4885CYP3A4 645/4885
US-20010039248-A1 Shaped bodies which release agrochemical active substances AGL, CHMP4B, GUSB ALDH1A1 758/4885HSD17B10 572/4885CYP3A4 686/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.