⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6688078 | 0.89 | HRH3 (0.32) | — | |
| SCHEMBL1414669 | 0.84 | — | — | |
| SCHEMBL2704923 | 0.82 | — | — | |
| SCHEMBL7338699 | 0.82 | CYP11B1 (0.33) | — | |
| SCHEMBL10628847 | 0.80 | ALDH1A1 (0.35) | — | |
| SCHEMBL10578679 | 0.72 | — | — | |
| SCHEMBL10377287 | 0.65 | — | — | |
| SCHEMBL9856415 | 0.65 | — | — | |
| SCHEMBL2705915 | 0.62 | — | — | |
| SCHEMBL717282 | 0.61 | BRD4 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0224059-B1 | AZETIDINONE DERIVATIVE AND PROCESS FOR PREPARING THE SAME | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1992-04-15 | — | — | EP | claimed |
| US-5081238-A | βmethyl azetidinone derivatives and stereoselective process for preparing the same | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1992-01-14 | — | — | US | claimed |
| EP-0224059-A1 | Azetidinone derivative and process for preparing the same | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1987-06-03 | — | — | EP | claimed |
| JP-62103063-A | — | — | None | — | — | JP | disclosed |
| EP-0869944-A1 | N-ACYLPIPERIDINYLCARBONYLAMINOCARBOXYLIC ACIDS AND THEIR USE AS GLYCOPROTEIN IIB/IIa ANTAGONISTS AND FIBRINOGEN-BLOOD PLATELETS BINDING INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-14 | — | — | EP | disclosed |
| EP-0224059-B1 | AZETIDINONE DERIVATIVE AND PROCESS FOR PREPARING THE SAME | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1992-04-15 | — | — | EP | disclosed |
| US-5081238-A | βmethyl azetidinone derivatives and stereoselective process for preparing the same | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1992-01-14 | — | — | US | disclosed |
| EP-0224059-A1 | Azetidinone derivative and process for preparing the same | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1987-06-03 | — | — | EP | disclosed |
| JP-S62103063-A | AZETIDINONE DERIVATIVE AND PRODUCTION THEREOF | SAGAMI CHEM RES CENTER | 1987-05-13 | — | — | JP | disclosed |