SCHEMBL717282

SCHEMBL717282

C#CN1C(=O)CCCC1=O

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.35
BRD2 P25440 1/20 0.35
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9856415 0.88
SCHEMBL9550315 0.72 CTSL (0.35) BRD4BRD2KMT2A
SCHEMBL721016 0.69 BRD4 (0.37) BRD4BRD2KMT2A
SCHEMBL1414669 0.69
SCHEMBL3880356 0.67 CHRM2 (0.45) KMT2A
SCHEMBL2704923 0.67
SCHEMBL10628847 0.65 ALDH1A1 (0.35) BRD4BRD2KMT2A
SCHEMBL1414198 0.63
SCHEMBL9643829 0.63
SCHEMBL8660593 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0263492-B1 RETINOIDS, THEIR PREPARATION AND USE AS PHARMACEUTICAL COMPOUNDS F. HOFFMANN-LA ROCHE AG (CH) 1991-03-13 EP claimed
US-9150414-B2 Nanocomposite and dispersion comprising the same KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) 2015-10-06 US disclosed
US-20120053288-A1 NANOCOMPOSITE AND DISPERSION COMPRISING THE SAME KABUSHIKI KAISHA TOYOTA CHUO KENKYUSHO (JP) 2012-03-01 US disclosed