Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAGI3 | Q5TCQ9 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | EDNRA | P25101 | 1/20 | 0.49 |
| ▸ | ACE | P12821 | 2/20 | 0.49 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MPO | P05164 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | KISS1R | Q969F8 | 5/20 | 0.46 |
| ▸ | ECE1 | P42892 | 3/20 | 0.46 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30130527 | 0.97 | MAGI3 (0.54) | MAGI3KMT2AL3MBTL1EDNRAACE | |
| SCHEMBL30093012 | 0.97 | MAGI3 (0.54) | MAGI3KMT2AL3MBTL1EDNRAACE | |
| SCHEMBL30093068 | 0.97 | MAGI3 (0.54) | MAGI3KMT2AL3MBTL1EDNRAACE | |
| SCHEMBL30130582 | 0.94 | EDNRA (0.57) | MAGI3EDNRAKISS1R | |
| SCHEMBL30130532 | 0.92 | MAGI3 (0.54) | MAGI3KMT2AL3MBTL1EDNRAACE | |
| SCHEMBL30092943 | 0.92 | KISS1R (0.56) | MAGI3EDNRAKISS1RECE1 | |
| SCHEMBL29989836 | 0.92 | NPBWR1 (0.55) | PRMT1KISS1RECE1NPBWR1 | |
| SCHEMBL11811768 | 0.92 | MAGI3 (0.54) | MAGI3KMT2AL3MBTL1EDNRAACE | |
| SCHEMBL30092978 | 0.92 | EDNRA (0.55) | MAGI3KMT2AL3MBTL1EDNRAACE | |
| SCHEMBL30093029 | 0.92 | EDNRA (0.57) | MAGI3EDNRAKISS1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5741668-A | SYNTHESIZING COELENTERAZINE, A BIOLUMINESCENT COMPOUND | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 1998-04-21 | — | — | US | disclosed |
| WO-1995021191-A1 | BIOLUMINESCENT INDICATOR BASED UPON THE EXPRESSION OF A GENE FOR A MODIFIED GREEN-FLUORESCENT PROTEIN | WARD WILLIAM (US) | 1995-08-10 | — | — | WO | disclosed |