Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | DRD2 | P14416 | 2/20 | 0.50 |
| ▸ | DRD4 | P21917 | 2/20 | 0.50 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.50 |
| ▸ | DRD3 | P35462 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KCNA3 | P22001 | 6/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5495026 | 0.82 | ATM (0.55) | ATMDRD2DRD4OPRM1DRD3 | |
| SCHEMBL5857455 | 0.80 | ATM (0.57) | ATMDRD2DRD4OPRM1DRD3 | |
| SCHEMBL1508107 | 0.80 | ATM (0.37) | ATMDRD2DRD4OPRM1DRD3 | |
| SCHEMBL10624241 | 0.79 | ALDH1A1 (0.48) | ATMDRD2DRD4OPRM1DRD3 | |
| SCHEMBL10796236 | 0.78 | ATM (0.55) | ATMDRD2DRD4OPRM1DRD3 | |
| SCHEMBL1508046 | 0.78 | KCNN4 (0.41) | ATMDRD2DRD4OPRM1DRD3 | |
| SCHEMBL6258542 | 0.78 | DRD2 (0.68) | ATMDRD2DRD4OPRM1DRD3 | |
| SCHEMBL5779039 | 0.76 | ALDH1A1 (0.46) | ATMDRD2DRD4OPRM1DRD3 | |
| SCHEMBL7345657 | 0.76 | HTT (0.47) | ATMDRD2DRD4OPRM1DRD3 | |
| SCHEMBL3979738 | 0.74 | CYP2D6 (0.58) | ATMDRD2DRD4OPRM1DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0875762-A2 | Immunogens for raising antibodies useful in methadone fluorescence polarization immunoassay | Abbott Laboratories (US) | 1998-11-04 | — | — | EP | disclosed |
| EP-0380019-B1 | Methadone fluorescence polarization immunoassay | ABBOTT LAB (US) | 1995-11-08 | — | — | EP | disclosed |
| EP-0662613-A1 | Immunogens for raising antibodies useful in methadone fluorescence polarization immunoassay | ABBOTT LABORATORIES (US) | 1995-07-12 | — | — | EP | disclosed |
| US-5073629-A | Haptens attached to immunogenic carrier; quantitative analysis , drugs testing | ABBOTT LABORATORIES (US) | 1991-12-17 | — | — | US | disclosed |
| EP-0380019-A2 | Methadone fluorescence polarization immunoassay | ABBOTT LABORATORIES (US) | 1990-08-01 | — | — | EP | disclosed |
| US-4548994-A | IMMOBILIZATION ON AFFINITY RESIN | THE UPJOHN COMPANY (US) | 1985-10-22 | — | — | US | disclosed |
| EP-0057600-B1 | AFFINITY RESINS AND THEIR USE IN ISOLATING BACTERIAL LUCIFERASE | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 1985-05-08 | — | — | EP | disclosed |
| US-4412001-A | IMMOBILIZATION BY BINDING TO A LIGAND-SPACER-SUPPORT; WASHING; DESORPTION; PURIFICATION | BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) | 1983-10-25 | — | — | US | disclosed |