SCHEMBL8660792

SCHEMBL8660792

CC1=C(c2ccccc2)C(=O)N(C(C)(C)c2cccc(OC(F)F)c2)CO1

nearest known ligand 0.33

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
DRD1 P21728 1/20 0.33
PPARG P37231 1/20 0.33
PPARA Q07869 1/20 0.33
KMT2A Q03164 1/20 0.32
NPSR1 Q6W5P4 2/20 0.32
RORC P51449 1/20 0.32
KCNA5 P22460 1/20 0.32
KCNH2 Q12809 1/20 0.32
ACSS2 Q9NR19 1/20 0.32
CTSD P07339 1/20 0.31
BACE1 P56817 1/20 0.31
KDM4E B2RXH2 1/20 0.31
SMN1; SMN2 Q16637 2/20 0.31
PDE2A O00408 1/20 0.31
TAS2R14 Q9NYV8 1/20 0.31
KDR P35968 1/20 0.31
GRM2 Q14416 1/20 0.31
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8663046 0.83 PTGS1 (0.34) KMT2A
SCHEMBL8660051 0.82 CNR1 (0.35) KMT2AKCNH2SMN1; SMN2
SCHEMBL7209835 0.82 KMT2A (0.36) KMT2ASMN1; SMN2
SCHEMBL8206162 0.81 PTGS2 (0.36) KMT2AKDM4ESMN1; SMN2GAA
SCHEMBL8205870 0.79 NR3C1 (0.32) KMT2AKCNH2
SCHEMBL8659691 0.77 PTGS1 (0.42) KMT2A
SCHEMBL117855 0.76 CNR1 (0.32) KMT2AGAA
SCHEMBL8402082 0.73 KMT2A (0.33) KMT2ASMN1; SMN2
SCHEMBL9246074 0.73 KMT2A (0.31) KMT2A
SCHEMBL7209897 0.72 KMT2A (0.36) KMT2AKDM4ESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0657099-B1 Herbicidal composition RHONE POULENC AGROCHIMIE (FR) 1998-11-04 EP disclosed
EP-0708597-B1 HERBICIDAL COMPOSITIONS RHONE POULENC AGROCHIMIE (FR) 1998-09-16 EP disclosed
US-5672566-A MIXTURES OF 6-ALKYL-3-ALKYL(OR HALOALKYL-)PHENYL-5-PHENYL 2,3-DIHYDRO-4H-1,3-OXAZIN-4-ONES WITH OTHER HERBICIDES RHONE-POULENC AGROCHIMIE (FR) 1997-09-30 US disclosed
EP-0657099-A1 Herbicidal composition RHONE-POULENC AGROCHIMIE (FR) 1995-06-14 EP disclosed