SCHEMBL866089

SCHEMBL866089

C=C(CC1CO1)C(=O)OCCCCCCCCCCCC

nearest known ligand 0.54

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.54
ALDH1A1 P00352 3/20 0.46
TDP1 Q9NUW8 1/20 0.46
NAAA Q02083 3/20 0.42
RAD52 P43351 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
EPHX1 P07099 1/20 0.40
GBA2 Q9HCG7 1/20 0.38
GAA P10253 1/20 0.38
MAPK1 P28482 1/20 0.38
HTT P42858 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28274192 0.98 TSHR (0.51) TSHRALDH1A1TDP1NAAARAD52
SCHEMBL1685769 0.94 TSHR (0.45) TSHRALDH1A1TDP1SMN1; SMN2
SCHEMBL9562354 0.87 ALDH1A1 (0.46) TSHRALDH1A1TDP1SMN1; SMN2
SCHEMBL1241845 0.85 ALDH1A1 (0.44) TSHRALDH1A1TDP1NAAASMN1; SMN2
SCHEMBL1491281 0.84 ALDH1A1 (0.40) TSHRALDH1A1
SCHEMBL10456432 0.84 ALDH1A1 (0.47) TSHRALDH1A1
SCHEMBL27764502 0.83 TSHR (0.45) TSHRALDH1A1TDP1GAASMN1; SMN2
SCHEMBL9130197 0.83 ALDH1A1 (0.41) TSHRALDH1A1
SCHEMBL2313682 0.83 ALDH1A1 (0.41) TSHRALDH1A1
SCHEMBL3951265 0.82 TSHR (0.42) TSHRALDH1A1EPHX1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115190871-A Reduced coating diameter chlorine doped silica optical fiber with low loss and microbending sensitivity 康宁股份有限公司 2022-10-14 CN disclosed
CN-114930218-A Reduced radius optical fiber with high mechanical reliability 康宁股份有限公司 2022-08-19 CN disclosed
CN-114845967-A Optical fiber coating with low pullout force 康宁股份有限公司 2022-08-02 CN disclosed
CN-113728259-A Reduced diameter multimode optical fiber resistant to puncture 康宁股份有限公司 2021-11-30 CN disclosed
CN-113711096-A Multimode optical fiber with reduced cladding thickness 康宁股份有限公司 2021-11-26 CN disclosed
CN-112782801-A Low diameter optical fiber 康宁股份有限公司 2021-05-11 CN disclosed
CN-110546119-B Method for applying coating liquid to optical fiber 康宁股份有限公司 2021-02-19 CN disclosed
CN-112074493-A Optical fiber coating with low pullout force 康宁股份有限公司 2020-12-11 CN disclosed
CN-111650686-A Low diameter optical fiber 康宁股份有限公司 2020-09-11 CN disclosed
US-10273324-B2 Polyvinylamide polymers containing polymerizable functionalities ISP INVESTMENTS LLC (US) 2019-04-30 US disclosed
US-20120077893-A1 Premixes Suitable for the Production of Membrane Materials ISP INVESTMENTS INC. (US) 2012-03-29 US disclosed
US-20110245409-A1 Polyvinylamide Polymers Containing Polymerizable Functionalities ASHLAND LICENSING AND INTELLECTUAL PROPERTY LLC 2011-10-06 US disclosed
WO-2010111607-A1 PREMIXES SUITABLE FOR THE PRODUCTION OF MEMBRANE MATERIALS ISP INVESTMENTS INC. (US) 2010-09-30 WO disclosed
US-20100190947-A1 POLYVINYLAMIDE POLYMERS CONTAINING POLYMERIZABLE FUNCTIONALITIES ISP INVESTMENTS LLC 2010-07-29 US disclosed
EP-2201051-A1 POLYVINYLAMIDE POLYMERS CONTAINING POLYMERIZABLE FUNCTIONALITIES Isp Investments Inc. (US) 2010-06-30 EP disclosed
EP-1189994-B1 OIL SOLUBLE RADIATION CURABLE METAL-CONTAINING COMPOUNDS AND COMPOSITIONS SARTOMER CO INC (US) 2009-03-18 EP disclosed
WO-2009023843-A1 POLYVINYLAMIDE POLYMERS CONTAINING POLYMERIZABLE FUNCTIONALITIES ISP INVESTMENTS INC. (US) 2009-02-19 WO disclosed
US-6399672-B1 OIL SOLUBLE UNSATURATED COMPOUNDS AND PHOTOINITIATORS SARTOMER TECHNOLOGIES CO., INC. 2002-06-04 US disclosed
EP-1189994-A2 OIL SOLUBLE RADIATION CURABLE METAL-CONTAINING COMPOUNDS AND COMPOSITIONS SARTOMER COMPANY, INC. (US) 2002-03-27 EP disclosed
WO-2000075241-A2 OIL SOLUBLE RADIATION CURABLE METAL-CONTAINING COMPOUNDS AND COMPOSITIONS SARTOMER COMPANY, INC. (US) 2000-12-14 WO disclosed