Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | PLCG2 | P16885 | 1/20 | 0.44 |
| ▸ | PCTP | Q9UKL6 | 1/20 | 0.44 |
| ▸ | PYGL | P06737 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | KIT | P10721 | 1/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.42 |
| ▸ | STK39 | Q9UEW8 | 1/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.41 |
| ▸ | PNLIP | P16233 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.40 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8657100 | 0.94 | GCGR (0.51) | GCGRNPC1RAB9APOLBPKM | |
| SCHEMBL8663074 | 0.90 | TAS1R3 (0.44) | GCGRNPC1MEN1KMT2ALRRK2 | |
| SCHEMBL8658093 | 0.89 | KIT (0.49) | GCGRNPC1RAB9APOLBPKM | |
| SCHEMBL8658727 | 0.86 | KDM4E (0.47) | NPC1TDP1MEN1KMT2A | |
| SCHEMBL8662551 | 0.85 | S1PR1 (0.47) | GCGRKITPDGFRAS1PR1 | |
| SCHEMBL8658837 | 0.84 | TAS1R3 (0.44) | GCGRNPC1KITPDGFRAMEN1 | |
| SCHEMBL8660988 | 0.84 | GCGR (0.55) | GCGRNPC1RAB9APOLBPKM | |
| SCHEMBL8660896 | 0.83 | KDM4E (0.46) | NPC1RAB9APKMTDP1MEN1 | |
| SCHEMBL8660995 | 0.82 | S1PR1 (0.53) | GCGRNPC1RAB9APOLBPKM | |
| SCHEMBL8659341 | 0.81 | KDM4E (0.47) | NPC1RAB9ATDP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776981-A | Use of acyl urea compounds for controlling endoparasites and ectoparasites of warm-blooded animals | NOVARTIS CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |
| US-5776982-A | Use of acyl urea compounds for controlling endoparasites and ectoparasites of warm-blooded animals | NOVARTIS CORPORATION (US) | 1998-07-07 | — | — | US | disclosed |
| US-5420163-A | Insecticides or miticides | CIBA-GEIGY (US) | 1995-05-30 | — | — | US | disclosed |
| US-5135953-A | Oral or injections; cattle, swine, poultry | CIBA-GEIGY (US) | 1992-08-04 | — | — | US | disclosed |
| US-4659724-A | Certain 1-[4-(5-cyano-2-pyridyloxy)phenyl-benzoyl ureas having pesticidal properties | UNION CARBIDE CORPORATION (US) | 1987-04-21 | — | — | US | disclosed |
| EP-0211004-A1 | USE OF ACYL UREA COMPOUNDS FOR CONTROLLING ENDOPARASITES AND ECTOPARASITES OF WARM-BLOODED ANIMALS | RHONE-POULENC NEDERLAND B.V. (NL) | 1987-02-25 | — | — | EP | disclosed |
| WO-1986003941-A1 | USE OF ACYL UREA COMPOUNDS FOR CONTROLLING ENDOPARASITES AND ECTOPARASITES OF WARM-BLOODED ANIMALS | UNION CARBIDE CORPORATION (US) | 1986-07-17 | — | — | WO | disclosed |
| EP-0115210-A1 | Pesticidal benzoyl ureas and process for their preparation | UNION CARBIDE CORPORATION (US) | 1984-08-08 | — | — | EP | disclosed |