SCHEMBL8660958

SCHEMBL8660958

NC(CC(=O)O)[N+](=O)[O-]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10417522 0.74 LMNA (0.46)
SCHEMBL2011902 0.72
D-Aspartate SCHEMBL31427183 0.71 GRIK1 (0.45)
Aspartic Acid SCHEMBL28896911 0.71 GRIK1 (0.45)
Aspartic Acid SCHEMBL31525181 0.71 GRIK1 (0.45)
Aspartic Acid SCHEMBL22440724 0.71 GRIK1 (0.45)
SCHEMBL5002407 0.70
SCHEMBL21989952 0.70 TDP1 (0.42)
SCHEMBL9388251 0.67
SCHEMBL1170869 0.67 ALDH1A1 (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0554363-B1 ALTERATION OF RATE AND CHARACTER OF HAIR GROWTH HANDELMAN JOSEPH H (US) 1998-06-24 EP claimed
EP-0554363-B1 ALTERATION OF RATE AND CHARACTER OF HAIR GROWTH HANDELMAN JOSEPH H (US) 1998-06-24 EP disclosed
EP-0554363-A4 ALTERATION OF RATE AND CHARACTER OF HAIR GROWTH 1993-09-15 EP disclosed
EP-0554363-A1 ALTERATION OF RATE AND CHARACTER OF HAIR GROWTH HANDELMAN, Joseph H. (US) 1993-08-11 EP disclosed
WO-1992007569-A1 ALTERATION OF RATE AND CHARACTER OF HAIR GROWTH HANDELMAN, JOSEPH, H. (US) 1992-05-14 WO disclosed
US-5095007-A Enzyme inhibitors GILLETTE COMPANY, THE 1992-03-10 US disclosed