Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.31 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.30 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.30 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8661130 | 0.83 | — | — | |
| SCHEMBL8663221 | 0.82 | KMT2A (0.34) | KMT2AKDM4EALDH1A1GLAGAA | |
| SCHEMBL8658182 | 0.82 | KDM4E (0.32) | KMT2AKDM4EALDH1A1GLAGAA | |
| SCHEMBL8659864 | 0.80 | — | — | |
| SCHEMBL8659685 | 0.78 | — | — | |
| SCHEMBL8668617 | 0.76 | FFAR1 (0.41) | FFAR1 | |
| SCHEMBL8846333 | 0.76 | FDFT1 (0.40) | KDM4EGLAFFAR1 | |
| SCHEMBL7660646 | 0.74 | FFAR1 (0.40) | FFAR1S1PR5 | |
| SCHEMBL8667563 | 0.74 | CYP4Z1 (0.37) | FFAR1 | |
| SCHEMBL8661991 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750693-A | THIOCHROMANYL OR CHROMANYL COMPOUNDS AS ANTICARCINOGINIC AGENTS, SKIN DISORDERS AND ATHEROSCLEROSIS | ALLERGAN (US) | 1998-05-12 | — | — | US | disclosed |