Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8664152 | 0.91 | MAP3K14 (0.32) | MAP3K14 | |
| SCHEMBL8663440 | 0.88 | MAP3K14 (0.30) | MAP3K14 | |
| SCHEMBL8661859 | 0.84 | PTGS2 (0.31) | — | |
| SCHEMBL8663438 | 0.84 | KDM4E (0.31) | KDM4EALDH1A1GLAGAAKMT2A | |
| SCHEMBL8659864 | 0.82 | — | — | |
| SCHEMBL8660965 | 0.82 | KMT2A (0.35) | KDM4EALDH1A1GLAGAAKMT2A | |
| SCHEMBL8658185 | 0.81 | NPC1 (0.31) | ALDH1A1GLAPRSS1PRSS2PRSS3 | |
| SCHEMBL8661130 | 0.81 | — | — | |
| SCHEMBL8663221 | 0.80 | KMT2A (0.34) | KDM4EALDH1A1GLAGAAKMT2A | |
| SCHEMBL7654818 | 0.80 | PRSS1 (0.33) | MAP3K14PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750693-A | THIOCHROMANYL OR CHROMANYL COMPOUNDS AS ANTICARCINOGINIC AGENTS, SKIN DISORDERS AND ATHEROSCLEROSIS | ALLERGAN (US) | 1998-05-12 | — | — | US | disclosed |
| US-5677451-A | CONTROLLING CELL DIFFERENTIATION; SKIN DISORDERS; ANTICANCER AGENTS | ALLERGAN (US) | 1997-10-14 | — | — | US | disclosed |