Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.38 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.35 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24088109 | 0.77 | HPRT1 (0.35) | CYP2A6ALDH1A1HSD17B10TSHRTDP1 | |
| SCHEMBL22416784 | 0.75 | MAPT (0.47) | CYP2A6ALDH1A1HSD17B10TSHRTDP1 | |
| SCHEMBL19033400 | 0.75 | ALDH1A1 (0.31) | CYP2A6ALDH1A1HSD17B10TSHRTDP1 | |
| SCHEMBL8891087 | 0.72 | HSD17B10 (0.39) | CYP2A6ALDH1A1HSD17B10TSHRTDP1 | |
| SCHEMBL3287319 | 0.71 | PAX8 (0.38) | CYP2A6ALDH1A1HSD17B10TSHRTDP1 | |
| SCHEMBL22129919 | 0.70 | CYP2A6 (0.52) | CYP2A6ALDH1A1HSD17B10TSHRTDP1 | |
| Hydrochloric Acid SCHEMBL25188851 | 0.70 | PAX8 (0.37) | CYP2A6ALDH1A1HSD17B10TSHRTDP1 | |
| SCHEMBL23280686 | 0.70 | ALDH1A1 (0.37) | CYP2A6ALDH1A1HSD17B10TSHRTDP1 | |
| SCHEMBL18810806 | 0.69 | — | — | |
| SCHEMBL8661137 | 0.68 | HPRT1 (0.36) | CYP2A6ALDH1A1HSD17B10TSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1247528-C | Novel tricyclic compounds, preparation method and pharmaceutical compositions containing same | SIRVIR LAB (FR) | 2006-03-29 | — | — | CN | claimed |
| CN-1285817-A | Novel tricyclic compounds, preparation method and pharmaceutical compositions containing same | ADIR (FR) | 2001-02-28 | — | — | CN | claimed |
| CN-108863957-A | Quinoxaline-fused dibenzocycloheptane spiro-ene compound and organic light emitting diode element | 杰秀有限公司 | 2018-11-23 | — | — | CN | disclosed |
| CN-1247528-C | Novel tricyclic compounds, preparation method and pharmaceutical compositions containing same | SIRVIR LAB (FR) | 2006-03-29 | — | — | CN | disclosed |
| CN-1285817-A | Novel tricyclic compounds, preparation method and pharmaceutical compositions containing same | ADIR (FR) | 2001-02-28 | — | — | CN | disclosed |
| US-5808154-A | Process for the production of an aromatic hydrazo compound | TOYO INK MANUFACTURING CO., LTD. (JP) | 1998-09-15 | — | — | US | disclosed |
| EP-0391606-B1 | Process for the production of an aromatic hydrazo compound | TOYO INK MFG CO (JP) | 1995-07-05 | — | — | EP | disclosed |
| EP-0391606-A1 | Process for the production of an aromatic hydrazo compound | TOYO INK MANUFACTURING CO., LTD. (JP) | 1990-10-10 | — | — | EP | disclosed |