Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 7/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8658261 | 0.83 | MAPT (0.53) | MAPTKMT2ANR3C2HDAC3HDAC4 | |
| SCHEMBL16896754 | 0.80 | MAPT (0.62) | MAPTKMT2ANR3C2HDAC3HDAC4 | |
| SCHEMBL9230551 | 0.74 | NR3C2 (0.52) | MAPTKMT2ANR3C2HDAC3HDAC4 | |
| SCHEMBL368343 | 0.73 | MAPT (1.00) | MAPTKMT2AHDAC3HDAC4HDAC1 | |
| Hydrochloric Acid SCHEMBL6174190 | 0.71 | MAPT (0.95) | MAPTKMT2AHDAC3HDAC4HDAC1 | |
| SCHEMBL7351483 | 0.71 | CA1 (0.48) | MAPTKMT2AHDAC3HDAC4HDAC1 | |
| SCHEMBL5674843 | 0.69 | MAPT (0.52) | MAPTKMT2ANR3C2HDAC3HDAC4 | |
| SCHEMBL2781433 | 0.69 | MAPT (0.68) | MAPTKMT2AHDAC3HDAC4HDAC1 | |
| SCHEMBL29159698 | 0.69 | MAPT (0.68) | MAPTKMT2AHDAC3HDAC4HDAC1 | |
| SCHEMBL2208266 | 0.68 | KMT2A (0.45) | MAPTKMT2ANR3C2HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0625516-B1 | Benzenesulphonamide derivatives for the treatment of bladder instability | ZENECA LTD (GB) | 1998-09-09 | — | — | EP | claimed |
| EP-0625516-A1 | Benzenesulphonamide derivatives for the treatment of bladder instability | ZENECA LIMITED (GB) | 1994-11-23 | — | — | EP | claimed |
| EP-0625516-B1 | Benzenesulphonamide derivatives for the treatment of bladder instability | ZENECA LTD (GB) | 1998-09-09 | — | — | EP | disclosed |
| EP-0625516-A1 | Benzenesulphonamide derivatives for the treatment of bladder instability | ZENECA LIMITED (GB) | 1994-11-23 | — | — | EP | disclosed |