Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHCY | P23526 | 11/20 | 0.69 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.65 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.65 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.65 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.61 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.61 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.61 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.61 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.61 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | BLM | P54132 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8661748 | 1.00 | AHCY (0.69) | AHCYHIF1ATMEM97SIGMAR1HSP90B1 | |
| SCHEMBL31680251 | 0.88 | AHCY (0.68) | AHCYHIF1ATMEM97SIGMAR1HSP90B1 | |
| SCHEMBL397800 | 0.88 | AHCY (0.68) | AHCYHIF1ATMEM97SIGMAR1HSP90B1 | |
| SCHEMBL6671788 | 0.87 | AHCY (0.67) | AHCYHIF1ATMEM97SIGMAR1HSP90B1 | |
| SCHEMBL7803295 | 0.87 | AHCY (0.67) | AHCYHIF1ATMEM97SIGMAR1HSP90B1 | |
| SCHEMBL2040666 | 0.86 | PRMT5 (0.66) | AHCYHIF1ATMEM97SIGMAR1HSP90B1 | |
| SCHEMBL5327602 | 0.86 | AHCY (0.65) | AHCYHIF1ATMEM97SIGMAR1HSP90B1 | |
| SCHEMBL22326787 | 0.85 | PRMT5 (0.64) | AHCYHIF1ATMEM97SIGMAR1HSP90B1 | |
| SCHEMBL13173634 | 0.85 | PRMT5 (0.64) | AHCYHIF1ATMEM97SIGMAR1HSP90B1 | |
| SCHEMBL22326785 | 0.85 | PRMT5 (0.64) | AHCYHIF1ATMEM97SIGMAR1HSP90B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0750489-B1 | INHIBITION OF HAIR GROWTH | HANDELMAN JOSEPH H (US) | 1998-11-18 | — | — | EP | claimed |
| EP-0750489-A1 | INHIBITION OF HAIR GROWTH | HANDELMAN, Joseph H. (US) | 1997-01-02 | — | — | EP | claimed |
| US-5455234-A | Applying inhibitor of cysteine pathway enzyme topically to skin; cosmetic for face, arms, legs | AHLUWALIA GURPREET S (US) | 1995-10-03 | — | — | US | claimed |
| WO-1995024885-A1 | INHIBITION OF HAIR GROWTH | HANDELMAN, JOSEPH, H. (US) | 1995-09-21 | — | — | WO | claimed |
| EP-3266784-A1 | PROTEIN ARGININE N-METHYLTRANSFERASES INHIBITORS AND USES THEREOF | PIERRE FABRE MEDICAMENT (FR) | 2018-01-10 | — | — | EP | disclosed |
| WO-2017211958-A1 | PROTEIN ARGININE N-METHYLTRANSFERASES INHIBITORS AND USES THEREOF | PIERRE FABRE MEDICAMENT (FR) | 2017-12-14 | — | — | WO | disclosed |
| EP-0750489-B1 | INHIBITION OF HAIR GROWTH | HANDELMAN JOSEPH H (US) | 1998-11-18 | — | — | EP | disclosed |
| EP-0750489-A1 | INHIBITION OF HAIR GROWTH | HANDELMAN, Joseph H. (US) | 1997-01-02 | — | — | EP | disclosed |
| US-5455234-A | Applying inhibitor of cysteine pathway enzyme topically to skin; cosmetic for face, arms, legs | AHLUWALIA GURPREET S (US) | 1995-10-03 | — | — | US | disclosed |
| WO-1995024885-A1 | INHIBITION OF HAIR GROWTH | HANDELMAN, JOSEPH, H. (US) | 1995-09-21 | — | — | WO | disclosed |