Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
| ▸ | HRH2 | P25021 | 2/20 | 0.31 |
| ▸ | HRH1 | P35367 | 2/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8656289 | 0.97 | OPRL1 (0.33) | OPRL1ITGB3ITGA2B | |
| SCHEMBL8660886 | 0.94 | ITGB3 (0.32) | GAAPKMITGB3ITGA2BKDM1A | |
| SCHEMBL8659278 | 0.92 | SMN1; SMN2 (0.39) | GAAHRH2HRH1ALDH1A1KDM1A | |
| SCHEMBL8655456 | 0.92 | SMN1; SMN2 (0.34) | GAAHRH2HRH1ALDH1A1KDM1A | |
| SCHEMBL8654586 | 0.90 | TPSAB1 (0.33) | PKMSMN1; SMN2 | |
| SCHEMBL8655367 | 0.90 | TPSAB1 (0.33) | PKMSMN1; SMN2 | |
| SCHEMBL8658988 | 0.90 | SMN1; SMN2 (0.38) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL8655360 | 0.90 | SMN1; SMN2 (0.34) | SMN1; SMN2 | |
| SCHEMBL8656871 | 0.89 | ITGB3 (0.32) | GAAPKMITGB3ITGA2BALDH1A1 | |
| SCHEMBL8659077 | 0.89 | GAA (0.34) | GAAOPRL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776937-A | Adhesion receptor antagonists | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-07-07 | — | — | US | disclosed |