Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 13/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28643991 | 0.92 | ATM (0.43) | HCAR2ATMTSHRTHRBTP53 | |
| SCHEMBL28635178 | 0.92 | ATM (0.43) | HCAR2ATMTSHRTHRBTP53 | |
| SCHEMBL25422020 | 0.82 | HCAR2 (0.59) | HCAR2ATMTSHRTP53EGLN1 | |
| SCHEMBL8661909 | 0.82 | HCAR2 (0.59) | HCAR2ATMTSHRTP53EGLN1 | |
| SCHEMBL27550205 | 0.82 | HCAR2 (0.59) | HCAR2ATMTSHRTP53EGLN1 | |
| SCHEMBL8661906 | 0.81 | HCAR2 (0.50) | HCAR2TSHRTP53EGLN1EGLN3 | |
| SCHEMBL4439683 | 0.81 | HCAR2 (0.50) | HCAR2TSHRTP53EGLN1EGLN3 | |
| SCHEMBL8940099 | 0.81 | HCAR2 (0.50) | HCAR2TSHRTP53EGLN1EGLN3 | |
| SCHEMBL10837369 | 0.80 | HCAR2 (0.67) | HCAR2ATMTSHRMAPTRAB9A | |
| SCHEMBL2812266 | 0.79 | HCAR2 (0.60) | HCAR2ATMTSHRTP53EGLN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113490489-A | Monomethyl fumarate-carrier conjugates and methods of use thereof | 旗舰创业创新五公司 | 2021-10-08 | — | — | CN | disclosed |