Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7817655 | 0.91 | ACACB (0.32) | — | |
| SCHEMBL8659641 | 0.85 | — | — | |
| SCHEMBL9136509 | 0.85 | RARB (0.36) | HPGD | |
| SCHEMBL8659481 | 0.82 | PRSS1 (0.34) | HPGD | |
| SCHEMBL8664184 | 0.82 | CYP3A4 (0.33) | HPGD | |
| SCHEMBL8846542 | 0.81 | ALDH1A1 (0.33) | — | |
| SCHEMBL7651211 | 0.81 | CYP26A1 (0.37) | — | |
| SCHEMBL8662239 | 0.80 | CYP3A4 (0.35) | — | |
| SCHEMBL8662230 | 0.79 | CYP3A4 (0.36) | — | |
| SCHEMBL8865300 | 0.79 | AKR1B1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750693-A | THIOCHROMANYL OR CHROMANYL COMPOUNDS AS ANTICARCINOGINIC AGENTS, SKIN DISORDERS AND ATHEROSCLEROSIS | ALLERGAN (US) | 1998-05-12 | — | — | US | disclosed |
| US-5677451-A | CONTROLLING CELL DIFFERENTIATION; SKIN DISORDERS; ANTICANCER AGENTS | ALLERGAN (US) | 1997-10-14 | — | — | US | disclosed |