SCHEMBL866215

SCHEMBL866215

CCCCC(F)(F)[C](F)F

nearest known ligand 0.46

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CES2 O00748 4/20 0.46
LPAR1 Q92633 1/20 0.37
LPAR3 Q9UBY5 1/20 0.37
FAAH O00519 8/20 0.36
CES1 P23141 6/20 0.34
MEN1 O00255 1/20 0.34
CYP1A2 P05177 1/20 0.34
KMT2A Q03164 1/20 0.34
HSD17B10 Q99714 1/20 0.34
FDPS P14324 1/20 0.34
ESR1 P03372 1/20 0.32
ESR2 Q92731 1/20 0.32
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
TSHR P16473 1/20 0.32
EPHX1 P07099 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL959689 0.92 CES2 (0.56) CES2LPAR1LPAR3FAAHCES1
SCHEMBL13717050 0.90 CES2 (0.59) CES2LPAR1LPAR3FAAHCES1
SCHEMBL4077269 0.90 CES2 (0.59) CES2LPAR1LPAR3FAAHCES1
SCHEMBL866970 0.82
SCHEMBL15402656 0.74
SCHEMBL8436421 0.74 CES2 (0.43) CES2LPAR1LPAR3FAAHCES1
SCHEMBL12396593 0.74 CES2 (0.54) CES2LPAR1LPAR3FAAHCES1
SCHEMBL1706449 0.74 CES2 (0.54) CES2LPAR1LPAR3FAAHCES1
SCHEMBL27956206 0.74 CES2 (0.34) CES2LPAR1LPAR3FAAHCES1
SCHEMBL23825120 0.72 CES2 (0.41) CES2LPAR1LPAR3FAAHCES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110650947-B Methods and molecules 免疫医疗有限责任公司 2023-05-12 CN claimed
US-20210283141-A1 PYRROLOBENZODIAZEPINE CONJUGATES MEDIMMUNE LIMITED (GB) 2021-09-16 US claimed
EP-3801630-A1 PYRROLOBENZODIAZEPINE CONJUGATES MEDIMMUNE LIMITED (GB) 2021-04-14 EP claimed
CN-112203696-A Pyrrolobenzodiazepine conjugates 免疫医疗有限公司 2021-01-08 CN claimed
CN-110650947-A Methods and molecules 免疫医疗有限责任公司 2020-01-03 CN claimed
WO-2019224340-A1 PYRROLOBENZODIAZEPINE CONJUGATES MEDIMMUNE LIMITED (GB) 2019-11-28 WO claimed
CN-107209146-B Electrochemical gas sensor and electrolyte for electrochemical gas sensor 德尔格安全股份两合公司 2024-03-12 CN disclosed
US-20230321267-A1 Method And Molecules THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2023-10-12 US disclosed
WO-2023174773-A1 PHOTOALIGNING MATERIALS Rolic Technologies AG (CH) 2023-09-21 WO disclosed
US-11759526-B2 Method and molecules MEDIMMUNE, LLC (US) 2023-09-19 US disclosed
EP-4223319-A2 METHOD AND MOLECULES MedImmune, LLC (US) 2023-08-09 EP disclosed
EP-3630732-B1 METHOD AND MOLECULES MEDIMMUNE LLC (US) 2023-07-12 EP disclosed
CN-110650947-B Methods and molecules 免疫医疗有限责任公司 2023-05-12 CN disclosed
EP-1801097-A1 Photocrosslinkable materials Rolic AG (CH) 2007-06-27 EP disclosed
US-7217492-B2 Onium salt compound and radiation-sensitive resin composition JSR CORPORATION (JP) 2007-05-15 US disclosed
US-7210763-B2 Inkjet recording head and inkjet recording device FUJIFILM CORPORATION (JP) 2007-05-01 US disclosed
US-20050068367-A1 Inkjet recording head and inkjet recording device FUJI PHOTO FILM CO., LTD. (JP) 2005-03-31 US disclosed
US-20050062801-A1 Inkjet recording head and inkjet recording device FUJI PHOTO FILM CO., LTD. (JP) 2005-03-24 US disclosed
US-20050053861-A1 Onium salt compound and radiation-sensitive resin composition JSR CORPORATION (JP) 2005-03-10 US disclosed
US-3978079-A DIPHTHALIMIDO, DISUCCINIMIDO AND DIMALEIMIDO OXALATES AMERICAN CYANAMID COMPANY (US) 1976-08-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230321267-A1 Method And Molecules PAICS, EPCAM, SQLE CES2 90/4885LPAR1 402/4885LPAR3 356/4885
US-11759526-B2 Method and molecules PAICS, EPCAM, SQLE CES2 90/4885LPAR1 402/4885LPAR3 356/4885
US-20210283141-A1 PYRROLOBENZODIAZEPINE CONJUGATES LANCL1, CD79B, FCGR2A CES2 1492/4885LPAR1 1588/4885LPAR3 1660/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.