Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.61 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7691526 | 0.95 | LOXL2 (0.61) | LOXL2CYP19A1HTTPOLBALDH1A1 | |
| SCHEMBL30313059 | 0.86 | LOXL2 (0.52) | LOXL2CYP19A1HTTPOLBALDH1A1 | |
| SCHEMBL3508166 | 0.82 | LOXL2 (0.48) | LOXL2HTTPOLBALDH1A1TSHR | |
| SCHEMBL6203764 | 0.81 | LOXL2 (0.47) | LOXL2CYP19A1HTTPOLBALDH1A1 | |
| SCHEMBL13822319 | 0.81 | CA2 (0.53) | LOXL2HTTPOLBSMN1; SMN2 | |
| SCHEMBL8662292 | 0.81 | CYP3A4 (0.50) | LOXL2POLBALDH1A1TSHRCYP3A4 | |
| Hydrochloric Acid SCHEMBL30321335 | 0.80 | LOXL2 (0.46) | LOXL2HTTPOLBALDH1A1TSHR | |
| SCHEMBL29105464 | 0.79 | CXCR4 (0.41) | LOXL2HTTPOLBALDH1A1CYP3A4 | |
| SCHEMBL43922 | 0.79 | TSHR (0.67) | LOXL2POLBALDH1A1TSHRNPC1 | |
| SCHEMBL30504205 | 0.79 | TSHR (0.67) | LOXL2POLBALDH1A1TSHRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8569451-B2 | Affinity material | BIOTAGE AB (SE) | 2013-10-29 | — | — | US | disclosed |
| US-8569451-B2 | Affinity material | BIOTAGE AB (SE) | 2013-10-29 | — | — | US | disclosed |
| US-8569451-B2 | Affinity material | BIOTAGE AB (SE) | 2013-10-29 | — | — | US | disclosed |
| EP-2419452-B1 | AFFINITY MATERIAL | BIOTAGE AB (SE) | 2013-08-21 | — | — | EP | disclosed |
| EP-2419452-B1 | AFFINITY MATERIAL | BIOTAGE AB (SE) | 2013-08-21 | — | — | EP | disclosed |
| US-20120095165-A1 | AFFINITY MATERIAL | BIOTAGE AB (SE) | 2012-04-19 | — | — | US | disclosed |
| US-20120095165-A1 | AFFINITY MATERIAL | BIOTAGE AB (SE) | 2012-04-19 | — | — | US | disclosed |
| US-20120095165-A1 | AFFINITY MATERIAL | BIOTAGE AB (SE) | 2012-04-19 | — | — | US | disclosed |
| EP-2419452-A1 | AFFINITY MATERIAL | Biotage AB (SE) | 2012-02-22 | — | — | EP | disclosed |
| WO-2010118985-A1 | AFFINITY MATERIAL | MIP TECHNOLOGIES AB (SE) | 2010-10-21 | — | — | WO | disclosed |
| WO-2010118985-A1 | AFFINITY MATERIAL | MIP TECHNOLOGIES AB (SE) | 2010-10-21 | — | — | WO | disclosed |
| US-20070112180-A1 | Detection of biomolecules by sensitizer-linked substrates | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2007-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070112180-A1 | Detection of biomolecules by sensitizer-linked substrates | ABCG2, SPR, DERA | LOXL2 2301/4885CYP19A1 2466/4885HTT 824/4885 |
| US-20120095165-A1 | AFFINITY MATERIAL | FCGR3B, FCGR2A, FCGR1A | LOXL2 3435/4885CYP19A1 4578/4885HTT 3540/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.