Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | CDK2 | P24941 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzenesulfonamide SCHEMBL6561832 | 0.87 | CA1 (0.52) | POLBKMT2ACDK2 | |
| SCHEMBL19100236 | 0.85 | KDM4E (0.53) | KMT2AALDH1A1KDM4EL3MBTL1HTT | |
| SCHEMBL4752431 | 0.82 | MEN1 (0.52) | KMT2ARAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL8662298 | 0.81 | MEN1 (0.61) | KMT2ARAB9ANPC1KDM4ESMN1; SMN2 | |
| SCHEMBL30852801 | 0.78 | HPGD (0.53) | POLBKMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL6816234 | 0.77 | NAMPT (0.50) | KMT2ARAB9ANPC1 | |
| SCHEMBL4751754 | 0.76 | NPC1 (0.57) | KMT2ARAB9ANPC1SMN1; SMN2L3MBTL1 | |
| SCHEMBL561358 | 0.76 | ALDH1A1 (0.46) | KMT2AALDH1A1 | |
| SCHEMBL16879281 | 0.75 | CHRNB2 (0.60) | POLBKMT2AALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL10912483 | 0.75 | NPC1 (0.58) | KMT2ARAB9ANPC1SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12010990-B2 | Hydrophobic polymers as oil rheology modifiers for agrochemical formulations | DOW GLOBAL TECHNOLOGIES LLC (US) | 2024-06-18 | — | — | US | disclosed |
| US-20230101819-A1 | SMYD Inhibitors | EPIZYME INC (US) | 2023-03-30 | — | — | US | disclosed |
| US-20220095613-A1 | PROPYLENE OXIDE CAPPED LIQUID POLYMERIC SURFACTANTS FOR AGRICULTURAL COMPOSITIONS AND AGRICULTURAL COMPOSITIONS INCLUDING PESTICIDE | DOW GLOBAL TECHNOLOGIES LLC (US) | 2022-03-31 | — | — | US | disclosed |
| CN-110381737-B | Methods of controlling ALS-tolerant plant growth | 江苏龙灯化学有限公司 | 2022-03-11 | — | — | CN | disclosed |
| CN-108004235-B | Soybean event SYHT0H2 and compositions and methods for detection thereof | 先正达参股股份有限公司 | 2022-02-08 | — | — | CN | disclosed |
| CN-113453549-A | Propylene oxide capped liquid polymeric surfactants for agricultural compositions and agricultural compositions including pesticides | 陶氏环球技术有限责任公司 | 2021-09-28 | — | — | CN | disclosed |
| US-20210198252-A1 | SMYD INHIBITORS | EPIZYME INC (US) | 2021-07-01 | — | — | US | disclosed |
| CN-111372453-A | Hydrophobic polymers as oil rheology modifiers for agrochemical formulations | 陶氏环球技术有限责任公司 | 2020-07-03 | — | — | CN | disclosed |
| US-20190322660-A1 | SMYD INHIBITORS | Epizyme, Inc. | 2019-10-24 | — | — | US | disclosed |
| US-10266526-B2 | Substituted 1,2,3-triazoles as SMYD inhibitors for treating cancer | Epizyme, Inc. (US) | 2019-04-23 | — | — | US | disclosed |
| US-20170355695-A1 | SMYD Inhibitors | Epizyme, Inc. (US) | 2017-12-14 | — | — | US | disclosed |
| EP-1910316-A1 | SUBSTITUTED TRIAZOLE DERIVATIVES AND THEIR USE AS NEUROKININ 3 RECEPTOR ANTAGONISTS | F. Hoffmann-Roche AG (CH) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007012579-A1 | SUBSTITUTED TRIAZOLE DERIVATIVES AND THEIR USE AS NEUROKININ 3 RECEPTOR ANTAGONISTS | F. HOFFMANN-LA ROCHE AG (CH) | 2007-02-01 | — | — | WO | disclosed |
| US-6967212-B2 | Substituted azole acid derivatives useful as antidiabetic and antiobesity agents and method | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-11-22 | — | — | US | disclosed |
| US-20050124661-A1 | Substituted azole acid derivatives useful as antidiabetic and antiobesity agents and method | CHENG PETER T (US) | 2005-06-09 | — | — | US | disclosed |
| EP-1390363-A2 | SUBSTITUTED AZOLE ACID DERIVATIVES USEFUL AS ANTIDIABETIC AND ANTIOBESITY AGENTS AND METHOD | Bristol-Myers Squibb Company (US) | 2004-02-25 | — | — | EP | disclosed |
| US-20030158232-A1 | Substituted azole acid derivatives useful as antidiabetic and antiobesity agents and method | BRISTOL-MYERS SQUIBB COMPANY | 2003-08-21 | — | — | US | disclosed |
| US-20030092736-A1 | Substituted azole acid derivatives useful as antidiabetic and antiobesity agents and method | BRISTOL-MYERS SQUIBB COMPANY | 2003-05-15 | — | — | US | disclosed |
| WO-2002096358-A2 | SUBSTITUTED AZOLE ACID DERIVATIVES USEFUL AS ANTIDIABETIC AND ANTIOBESITY AGENTS AND METHOD | BRISTOL-MYERS SQUIBB COMPANY (US) | 2002-12-05 | — | — | WO | disclosed |
| US-5990043-A | COMPRISES AT LEAST ONE INSECTICIDE SELECTED FROM TRIFLUMURON, FLUFENOXURON, FLUCYCLOXURON, HEXAFLUMURON, AND OTHERS; A CARRIER AND BINDER; PROTECTS ITEMS SUCH AS SHIP HULLS IN BRACKISH OR SEAWATER FROM BARNICLE INFESTATIONS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-11-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12010990-B2 | Hydrophobic polymers as oil rheology modifiers for agrochemical formulations | DDT, NAPEPLD, LIPA | POLB 3413/4885KMT2A 2947/4885RAB9A 3863/4885 |
| US-20030158232-A1 | Substituted azole acid derivatives useful as antidiabetic and antiobesity agents and method | GPR119, PPARA, PPARG | POLB 3598/4885KMT2A 1491/4885RAB9A 1545/4885 |
| US-20030092736-A1 | Substituted azole acid derivatives useful as antidiabetic and antiobesity agents and method | GPR119, PPARA, PPARG | POLB 3598/4885KMT2A 1491/4885RAB9A 1545/4885 |
| US-10266526-B2 | Substituted 1,2,3-triazoles as SMYD inhibitors for treating cancer | SMYD3, SMYD2, SNRPD3 | POLB 4315/4885KMT2A 360/4885RAB9A 1388/4885 |
| US-20170355695-A1 | SMYD Inhibitors | SMYD3, SMYD2, SMURF2 | POLB 4153/4885KMT2A 348/4885RAB9A 893/4885 |
| US-20210198252-A1 | SMYD INHIBITORS | SMYD3, SMYD2, SMURF2 | POLB 4132/4885KMT2A 355/4885RAB9A 890/4885 |
| US-20190322660-A1 | SMYD INHIBITORS | SMYD2, SMYD3, SMURF2 | POLB 4325/4885KMT2A 420/4885RAB9A 736/4885 |
| US-20050124661-A1 | Substituted azole acid derivatives useful as antidiabetic and antiobesity agents and method | GPR119, PPARA, PPARG | POLB 1611/4885KMT2A 1144/4885RAB9A 2588/4885 |
| US-20230101819-A1 | SMYD Inhibitors | SMYD3, SMYD2, SMURF2 | POLB 4195/4885KMT2A 364/4885RAB9A 914/4885 |
| US-20220095613-A1 | PROPYLENE OXIDE CAPPED LIQUID POLYMERIC SURFACTANTS FOR AGRICULTURAL COMPOSITIONS AND AGRICULTURAL COMPOSITIONS INCLUDING PESTICIDE | PAOX, PHOSPHO1, NAPEPLD | POLB 981/4885KMT2A 4167/4885RAB9A 4491/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.