Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 10/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8664226 | 0.84 | CCKBR (0.57) | CCKBR | |
| SCHEMBL8561164 | 0.79 | CCKBR (0.59) | CCKBR | |
| SCHEMBL8662406 | 0.72 | CCKBR (0.40) | CCKBREPHX1EPHX2RAB9ASMN1; SMN2 | |
| SCHEMBL8648076 | 0.70 | CCKBR (0.64) | CCKBR | |
| SCHEMBL1387951 | 0.70 | CCKBR (0.62) | CCKBR | |
| SCHEMBL7738118 | 0.66 | CCKBR (0.56) | CCKBR | |
| SCHEMBL8561705 | 0.64 | CCKBR (0.47) | CCKBR | |
| SCHEMBL7466224 | 0.61 | CCKBR (0.59) | CCKBRRAB9A | |
| SCHEMBL7610054 | 0.59 | CCKBR (0.55) | CCKBR | |
| SCHEMBL7610061 | 0.59 | CCKBR (0.55) | CCKBR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710230-B1 | 1,5-BENZODIAZEPINE DERIVATIVES USEFUL AS CCK OR GASTRIN ANTAGONISTS | GLAXO WELLCOME SPA (IT) | 1998-09-16 | — | — | EP | claimed |