Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 5/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ICMT | O60725 | 1/20 | 0.35 |
| ▸ | ALB | P02768 | 1/20 | 0.35 |
| ▸ | CTSD | P07339 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | CCKAR | P32238 | 1/20 | 0.34 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.33 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.33 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8662408 | 0.72 | CCKBR (0.42) | CCKBREPHX1EPHX2RAB9ASMN1; SMN2 | |
| SCHEMBL8561164 | 0.71 | CCKBR (0.59) | CCKBR | |
| SCHEMBL8866205 | 0.69 | CCKBR (0.51) | CCKBR | |
| SCHEMBL8559320 | 0.69 | CCKBR (0.49) | CCKBR | |
| SCHEMBL7738117 | 0.66 | CCKBR (0.47) | CCKBR | |
| SCHEMBL8563328 | 0.63 | CCKBR (0.49) | CCKBR | |
| SCHEMBL8648076 | 0.62 | CCKBR (0.64) | CCKBRCCKAR | |
| SCHEMBL23432014 | 0.59 | EPHX1 (1.00) | EPHX1EPHX2RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL12196136 | 0.59 | EPHX1 (1.00) | EPHX1EPHX2RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL23431981 | 0.59 | EPHX1 (1.00) | EPHX1EPHX2RAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0710230-B1 | 1,5-BENZODIAZEPINE DERIVATIVES USEFUL AS CCK OR GASTRIN ANTAGONISTS | GLAXO WELLCOME SPA (IT) | 1998-09-16 | — | — | EP | claimed |