Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 4/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1054149 | 0.83 | NPSR1 (0.44) | NPSR1BRD4ALDH1A1CYP1A2KDM4E | |
| SCHEMBL30952862 | 0.83 | NPSR1 (0.44) | NPSR1BRD4ALDH1A1CYP1A2KDM4E | |
| SCHEMBL30401197 | 0.81 | NPSR1 (0.43) | KCNH2NPSR1BRD4ALDH1A1CYP1A2 | |
| SCHEMBL4859332 | 0.81 | NPSR1 (0.43) | KCNH2NPSR1BRD4ALDH1A1CYP1A2 | |
| SCHEMBL6898745 | 0.81 | KCNH2 (0.46) | KCNH2NPSR1BRD4ALDH1A1CYP1A2 | |
| SCHEMBL25537955 | 0.81 | KDM4E (0.53) | KCNH2BRD4CYP4F2CYP4A11KDM4E | |
| SCHEMBL874251 | 0.80 | CYP4F2 (0.41) | KCNH2NPSR1BRD4ALDH1A1CYP1A2 | |
| Alcohol SCHEMBL4865562 | 0.80 | NPSR1 (0.42) | KCNH2NPSR1BRD4ALDH1A1CYP1A2 | |
| SCHEMBL31013362 | 0.80 | ALDH1A1 (0.46) | KCNH2NPSR1BRD4ALDH1A1CYP1A2 | |
| SCHEMBL12432224 | 0.79 | IRAK4 (0.49) | KCNH2NPSR1BRD4ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5763461-A | ANTIPICORNAVIRAL AGENTS | SANOFI (FR) | 1998-06-09 | — | — | US | disclosed |
| US-5618821-A | VIRICIDES, PICORNAVIRUS | SANOFI, S.A. (FR) | 1997-04-08 | — | — | US | disclosed |
| WO-1995031438-A1 | THERAPEUTIC PHENOXYALKYLHETEROCYCLES | SANOFI WINTHROP, INC. (US) | 1995-11-23 | — | — | WO | disclosed |