Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 3/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8662483 | 0.80 | KCNH2 (0.43) | CYP4F2CYP4A11KCNH2BRD4NPSR1 | |
| SCHEMBL882632 | 0.80 | KCNH2 (0.36) | CYP4F2CYP4A11KCNH2IDO1NR3C2 | |
| SCHEMBL16164122 | 0.80 | KCNH2 (0.36) | CYP4F2CYP4A11KCNH2IDO1NR3C2 | |
| SCHEMBL4859332 | 0.76 | NPSR1 (0.43) | KCNH2BRD4NPSR1CYP1A2ALDH1A1 | |
| SCHEMBL6898745 | 0.76 | KCNH2 (0.46) | KCNH2BRD4NPSR1CYP1A2ALDH1A1 | |
| SCHEMBL20202796 | 0.76 | NPSR1 (0.43) | BRD4NPSR1CYP1A2ALDH1A1P2RX7 | |
| SCHEMBL30401197 | 0.76 | NPSR1 (0.43) | KCNH2BRD4NPSR1CYP1A2ALDH1A1 | |
| SCHEMBL27927802 | 0.75 | BRD4 (0.37) | CYP4F2CYP4A11BRD4NPSR1CYP1A2 | |
| SCHEMBL31013362 | 0.75 | ALDH1A1 (0.46) | KCNH2BRD4NPSR1CYP1A2ALDH1A1 | |
| SCHEMBL882995 | 0.74 | P2RX7 (0.40) | CYP4F2CYP4A11KCNH2CYP1A2P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2619181-A1 | NOVEL MICROBIOCIDES | Syngenta Participations AG (CH) | 2013-07-31 | — | — | EP | disclosed |
| WO-2012038521-A1 | NOVEL MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-03-29 | — | — | WO | disclosed |