Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9232571 | 0.76 | — | — | |
| SCHEMBL8661109 | 0.65 | POLB (0.30) | POLB | |
| SCHEMBL8754798 | 0.63 | GABRA1 (0.30) | — | |
| SCHEMBL6278626 | 0.63 | GABRA1 (0.41) | POLB | |
| SCHEMBL9286989 | 0.62 | CYP26A1 (0.32) | POLB | |
| SCHEMBL564052 | 0.61 | — | — | |
| SCHEMBL9279370 | 0.59 | PRSS1 (0.31) | — | |
| SCHEMBL5178926 | 0.58 | GABRA1 (0.47) | POLB | |
| SCHEMBL5486977 | 0.58 | GABRA1 (0.38) | POLB | |
| SCHEMBL44699 | 0.58 | GABRA1 (0.48) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0536036-B1 | Cardioprotective tocopherol analogs | MERRELL PHARMA INC (US) | 1998-02-25 | — | — | EP | disclosed |
| EP-0369874-B1 | Cardioprotective tocopherol analogs | MERRELL DOW PHARMA (US) | 1995-02-22 | — | — | EP | disclosed |