Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4Z1 | Q86W10 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | RARA | P10276 | 1/20 | 0.36 |
| ▸ | RARB | P10826 | 1/20 | 0.36 |
| ▸ | RARG | P13631 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP4F11 | Q9HBI6 | 1/20 | 0.36 |
| ▸ | CYP4F12 | Q9HCS2 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 8/20 | 0.35 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | FPR1 | P21462 | 1/20 | 0.32 |
| ▸ | FPR3 | P25089 | 1/20 | 0.32 |
| ▸ | GPR183 | P32249 | 1/20 | 0.32 |
| ▸ | APLNR | P35414 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | GPR65 | Q8IYL9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8670902 | 0.93 | CYP4Z1 (0.39) | CYP4Z1CYP3A4RARARARBRARG | |
| SCHEMBL8674175 | 0.89 | CYP3A4 (0.46) | CYP4Z1CYP3A4RARARARBRARG | |
| SCHEMBL8668889 | 0.89 | CYP4F2 (0.36) | CYP4Z1CYP3A4RARARARBRARG | |
| SCHEMBL8672295 | 0.88 | FDFT1 (0.40) | CYP4Z1CYP3A4RARARARBRARG | |
| SCHEMBL7653077 | 0.88 | CYP3A4 (0.42) | CYP4Z1CYP3A4RARARARBRARG | |
| SCHEMBL8659941 | 0.86 | FFAR1 (0.41) | CYP4Z1CYP3A4RARARARBRARG | |
| SCHEMBL7657889 | 0.86 | CYP3A4 (0.39) | CYP3A4RARARARBRARGKMT2A | |
| SCHEMBL7655963 | 0.85 | CYP4F2 (0.33) | CYP4Z1CYP3A4RARARARBRARG | |
| SCHEMBL7651219 | 0.84 | CYP4F2 (0.34) | CYP4Z1CYP3A4RARARARBRARG | |
| SCHEMBL8676360 | 0.84 | FDFT1 (0.36) | CYP4Z1CYP3A4RARARARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750693-A | THIOCHROMANYL OR CHROMANYL COMPOUNDS AS ANTICARCINOGINIC AGENTS, SKIN DISORDERS AND ATHEROSCLEROSIS | ALLERGAN (US) | 1998-05-12 | — | — | US | disclosed |
| US-5677451-A | CONTROLLING CELL DIFFERENTIATION; SKIN DISORDERS; ANTICANCER AGENTS | ALLERGAN (US) | 1997-10-14 | — | — | US | disclosed |