Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.49 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.49 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | LCK | P06239 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.47 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.47 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.47 |
| ▸ | RRM1 | P23921 | 1/20 | 0.46 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.46 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.44 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.44 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.44 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.44 |
| ▸ | LAP3 | P28838 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3024374 | 0.93 | GPR84 (0.55) | GRIK1GRIK2GPR84FFAR1MAPT | |
| SCHEMBL7193866 | 0.93 | GPR84 (0.55) | GRIK1GRIK2GPR84FFAR1MAPT | |
| SCHEMBL28303044 | 0.93 | GPR84 (0.55) | GRIK1GRIK2GPR84FFAR1MAPT | |
| SCHEMBL3100665 | 0.91 | GRIK1 (0.53) | GRIK1GRIK2GPR84FFAR1MAPT | |
| SCHEMBL2983835 | 0.91 | GRIK1 (0.53) | GRIK1GRIK2GPR84FFAR1MAPT | |
| SCHEMBL2983833 | 0.91 | GRIK1 (0.53) | GRIK1GRIK2GPR84FFAR1MAPT | |
| SCHEMBL341675 | 0.88 | GRIK1 (0.45) | GRIK1GRIK2GPR84FFAR1MAPT | |
| SCHEMBL29157044 | 0.87 | GRIK1 (0.44) | GRIK1GRIK2GPR84FFAR1MAPT | |
| SCHEMBL9634478 | 0.86 | GRIK1 (0.44) | GRIK1GRIK2GPR84FFAR1MAPT | |
| SCHEMBL28491046 | 0.82 | GABRR1 (0.48) | GRIK1GRIK2SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0649303-B1 | SUBSTITUTED ARGININES AND SUBSTITUTED HOMOARGININES AND USE THEREOF | CORNELL RES FOUNDATION INC (US) | 1998-11-25 | — | — | EP | disclosed |
| US-5453441-A | Enzyme inhibitors and hypertensive agents | CORNELL RESEARCH FOUNDATION, INC. (US) | 1995-09-26 | — | — | US | disclosed |
| US-5281627-A | Guanidine substituted arginines | CORNELL RESEARCH FOUNDATION, INC. (US) | 1994-01-25 | — | — | US | disclosed |