Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 2/20 | 0.53 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.53 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.53 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.53 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.50 |
| ▸ | PPARD | Q03181 | 1/20 | 0.50 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.50 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.50 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.46 |
| ▸ | LAP3 | P28838 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2983835 | 1.00 | GRIK1 (0.53) | GRIK1GRIK2SLC1A2SLC1A1GPR84 | |
| SCHEMBL2983833 | 1.00 | GRIK1 (0.53) | GRIK1GRIK2SLC1A2SLC1A1GPR84 | |
| SCHEMBL28303044 | 0.98 | GPR84 (0.55) | GRIK1GRIK2SLC1A2SLC1A1GPR84 | |
| SCHEMBL3024374 | 0.98 | GPR84 (0.55) | GRIK1GRIK2SLC1A2SLC1A1GPR84 | |
| SCHEMBL7193866 | 0.98 | GPR84 (0.55) | GRIK1GRIK2SLC1A2SLC1A1GPR84 | |
| SCHEMBL8662590 | 0.91 | GRIK1 (0.49) | GRIK1GRIK2SLC1A2SLC1A1GPR84 | |
| SCHEMBL21981372 | 0.89 | SLC1A2 (0.48) | GRIK1GRIK2SLC1A2SLC1A1GPR84 | |
| SCHEMBL4551050 | 0.88 | GPR84 (0.52) | GRIK1GRIK2SLC1A2SLC1A1GPR84 | |
| SCHEMBL4551049 | 0.88 | GPR84 (0.52) | GRIK1GRIK2SLC1A2SLC1A1GPR84 | |
| SCHEMBL4774070 | 0.85 | CA2 (0.52) | GRIK1GRIK2SLC1A2SLC1A1GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1885688-B1 | ASYMMETRIC HYDROGENATION FOR THE PREPARATION OF DIPHENYLALANINE DERIVATIVES | REDDY S LAB EU LTD DR (GB) | 2010-09-22 | — | — | EP | disclosed |