SCHEMBL866265

SCHEMBL866265

C=CC(=O)OC(F)(F)C1(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C1(F)F

nearest known ligand 0.31

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31
TP53 P04637 1/20 0.31
CYP3A4 P08684 1/20 0.31
MAPK1 P28482 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HIF1A Q16665 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15854411 0.96 ALDH1A1 (0.31) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
SCHEMBL8021549 0.75
SCHEMBL9008973 0.72
SCHEMBL221767 0.71
SCHEMBL21819966 0.71 ALDH1A1 (0.38) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
SCHEMBL340930 0.71 ALDH1A1 (0.37) ALDH1A1
Methane SCHEMBL4270398 0.69 ALDH1A1 (0.37) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
SCHEMBL6725111 0.69
SCHEMBL31612683 0.69 ALDH1A1 (0.37) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2
Ethylene SCHEMBL28239247 0.69 ALDH1A1 (0.37) ALDH1A1TP53CYP3A4MAPK1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 122 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111925477-B Preparation method of fluorine-containing thickening agent capable of thickening hydrochloric acid solution 中国石油化工股份有限公司 2022-05-03 CN claimed
US-10273377-B2 Superhydrophobic and oleophobic ceramic polymer composite coating UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2019-04-30 US claimed
US-20170174928-A1 Superhydrophobic and Oleophobic Ceramic Polymer Composite Coating UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2017-06-22 US claimed
US-9448219-B2 Electro-mechanical switches and methods of use thereof MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2016-09-20 US claimed
WO-2016014952-A1 SUPERHYDROPHOBIC AND OLEOPHOBIC CERAMIC POLYMER COMPOSITE COATING UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2016-01-28 WO claimed
US-8441081-B2 Electro-mechanical switches and methods of use thereof MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2013-05-14 US claimed
US-8299139-B1 Process and reactor for synthesis of ultra-high molecular weight acrylic polymers OVATION POLYMER TECHNOLOGY AND ENGINEERED MATERIALS, INC. (US) 2012-10-30 US claimed
WO-2010011733-A2 ELECTRO-MECHANICAL SWITCHES AND METHODS OF USE THEREOF MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2010-01-28 WO claimed
WO-2007145657-A2 INITIATED CHEMICAL VAPOR DEPOSITION OF VINYL POLYMERS FOR THE ENCAPSULATION OF PARTICLES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2007-12-21 WO claimed
CN-111406077-B Copolymers of halogenated olefins and halogenated comonomers 阿科玛股份有限公司 2024-07-05 CN disclosed
US-20240124632-A1 Method for Producing Fluorine-Containing Polymer and Composition CENTRAL GLASS COMPANY, LIMITED (JP) 2024-04-18 US disclosed
US-20240043593-A1 Fluorine-Containing Polymer CENTRAL GLASS COMPANY, LIMITED (JP) 2024-02-08 US disclosed
US-11597696-B2 Method for purifying polymerizable fluoromonomer by distillation CENTRAL GLASS COMPANY, LIMITED (JP) 2023-03-07 US disclosed
CN-115626961-A Polymers of haloalkyl and haloalkenyl ether (meth) acrylates 阿科玛股份有限公司 2023-01-20 CN disclosed
US-6329058-B1 INORGANIC PARTICLES CAPABLE OF MIXING WITH TRANSPARENT ORGANIC COMPOSITION, TITANIUM OXIDE AND CRYSTALS WITH ABSORPTION 3M INNOVATIVE PROPERTIES COMPANY 2001-12-11 US disclosed
EP-1103856-A1 Positive resist composition & process for forming resist pattern using same Central Glass Company, Limited (JP) 2001-05-30 EP disclosed
US-5822489-A CLADDING ON OPTICAL FIBER MADE OF A CURED MATERIAL COMPRISING A PERFLUOROPOLYETHER OR PERFLUOROHYDROCARBON BACKBONE END CAPPED WITH (METH)ACRYLATE GROUPS VIA URETHANE GROUPS LUCENT TECHNOLOGIES, INC. (US) 1998-10-13 US disclosed
EP-0851246-A1 Optical fiber clad with low refractive index photocured composition LUCENT TECHNOLOGIES INC. (US) 1998-07-01 EP disclosed
EP-0425305-B1 Radiation curable cladding compositions MINNESOTA MINING & MFG (US) 1994-12-28 EP disclosed
EP-0425305-A2 Radiation curable cladding compositions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1991-05-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11597696-B2 Method for purifying polymerizable fluoromonomer by distillation AFF1, AFF4, AFF2 ALDH1A1 950/4885TP53 3336/4885CYP3A4 664/4885
US-20240124632-A1 Method for Producing Fluorine-Containing Polymer and Composition PFAS, AFF2, AFF1 ALDH1A1 865/4885TP53 4248/4885CYP3A4 1747/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.