Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8664693 | 0.83 | HTR1D (0.72) | HTR1DHTR1B | |
| SCHEMBL8662842 | 0.83 | HTR1D (0.53) | HTR1DHTR1B | |
| SCHEMBL8151636 | 0.81 | HTR1D (1.00) | HTR1DHTR1B | |
| Oxalic Acid SCHEMBL8660714 | 0.80 | HTR1D (0.67) | HTR1DHTR1B | |
| SCHEMBL8804144 | 0.77 | HTR1D (0.76) | HTR1DHTR1B | |
| SCHEMBL8984395 | 0.74 | HTR1D (0.87) | HTR1DHTR1B | |
| SCHEMBL8660428 | 0.73 | HPGD (0.49) | HTR1DHTR1B | |
| SCHEMBL9047205 | 0.72 | HTR1A (0.85) | HTR1DHTR1B | |
| SCHEMBL1377300 | 0.71 | HTR1A (0.83) | HTR1DHTR1B | |
| SCHEMBL30468393 | 0.70 | HTR1A (0.67) | HTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5807857-A | Piperazine, piperidine and tetrahydropyridine derivative of indol-3-alkyl as 5-HT1D-α agonists | MERCK SHARP & DOHME LTD. (GB) | 1998-09-15 | — | — | US | disclosed |