Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8663358 | 0.86 | DAGLA (0.32) | HTTKDM4E | |
| SCHEMBL13244896 | 0.77 | LMNA (0.38) | HTTKDM4ELMNAL3MBTL1GAA | |
| SCHEMBL8665404 | 0.72 | — | — | |
| SCHEMBL8654554 | 0.71 | HTT (0.35) | HTT | |
| SCHEMBL2824744 | 0.68 | LMNA (0.40) | HTTKDM4ELMNAL3MBTL1 | |
| SCHEMBL1919893 | 0.60 | — | — | |
| SCHEMBL1901781 | 0.60 | SMN1; SMN2 (0.61) | KDM4ELMNA | |
| SCHEMBL8654119 | 0.57 | GAA (0.30) | GAA | |
| SCHEMBL11087599 | 0.57 | GLA (0.36) | KDM4ELMNAL3MBTL1 | |
| SCHEMBL8652103 | 0.57 | GAA (0.43) | KDM4ELMNAL3MBTL1GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811445-A | ANGIOTENSIN II INHIBITORS | ROUSSEL UCLAF (FR) | 1998-09-22 | — | — | US | disclosed |