Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KDM6B | O15054 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.33 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.33 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8543962 | 0.79 | MAPT (0.39) | GAATDP1HSP90AA1ESR2MAPT | |
| SCHEMBL3023228 | 0.74 | HSP90AA1 (0.39) | L3MBTL1TDP1HSP90AA1ESR2KDM4E | |
| SCHEMBL213561 | 0.72 | PIN1 (0.48) | TDP1HSP90AA1ESR2KDM4EALDH1A1 | |
| SCHEMBL948852 | 0.72 | GABRP (0.41) | TDP1HSP90AA1ESR2KDM4EALDH1A1 | |
| SCHEMBL3023200 | 0.71 | ALDH1A1 (0.38) | TDP1HSP90AA1ESR2KDM4EALDH1A1 | |
| SCHEMBL3032708 | 0.71 | GPR35 (0.37) | TDP1HSP90AA1ESR2KDM4EALDH1A1 | |
| SCHEMBL8077442 | 0.68 | PIN1 (0.37) | TDP1HSP90AA1ESR2ALDH1A1 | |
| SCHEMBL8077446 | 0.68 | PARP1 (0.38) | TDP1HSP90AA1ESR2MAPTKDM4E | |
| SCHEMBL11990814 | 0.67 | GAA (0.59) | GAANUDT1L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL21816328 | 0.67 | NOTUM (0.37) | TDP1HSP90AA1ESR2MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5811445-A | ANGIOTENSIN II INHIBITORS | ROUSSEL UCLAF (FR) | 1998-09-22 | — | — | US | disclosed |