Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.32 |
| ▸ | JAK3 | P52333 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8484892 | 0.95 | JAK3 (0.33) | GRIN2BGRIN2CCYP4F2CYP4A11JAK3 | |
| SCHEMBL27973224 | 0.83 | GRIN2B (0.40) | GRIN2BGRIN2CCYP4F2CYP4A11JAK3 | |
| SCHEMBL28670126 | 0.78 | JAK3 (0.33) | GRIN2BGRIN2CCYP4F2CYP4A11JAK3 | |
| SCHEMBL29200802 | 0.77 | GRIN2B (0.43) | GRIN2BGRIN2CJAK3CTSKUSP2 | |
| SCHEMBL3310180 | 0.75 | — | — | |
| SCHEMBL9358435 | 0.75 | — | — | |
| SCHEMBL9518563 | 0.74 | CYP4F2 (0.32) | GRIN2BGRIN2CCYP4F2CYP4A11JAK3 | |
| SCHEMBL1963765 | 0.74 | GRIN2B (0.32) | GRIN2BGRIN2CCYP4F2CYP4A11 | |
| SCHEMBL1772287 | 0.73 | CYP4F2 (0.39) | CYP4F2CYP4A11USP2SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL25356046 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5827875-A | PYRROLIDINE DERIVATIVES; ANTIATHEROSCLEROSIS AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-10-27 | — | — | US | disclosed |