Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9518563 | 0.80 | CYP4F2 (0.32) | GRIN2BGRIN2CCYP4F2CYP4A11 | |
| SCHEMBL28779766 | 0.78 | GRIN2B (0.36) | GRIN2BGRIN2CCYP4F2CYP4A11 | |
| SCHEMBL8663550 | 0.74 | GRIN2B (0.36) | GRIN2BGRIN2CCYP4F2CYP4A11 | |
| SCHEMBL7382306 | 0.70 | CYP4F2 (0.33) | CYP4F2CYP4A11 | |
| SCHEMBL2216266 | 0.70 | HPGD (0.33) | CYP4F2CYP4A11 | |
| SCHEMBL8585741 | 0.70 | HPGD (0.33) | CYP4F2CYP4A11 | |
| SCHEMBL630080 | 0.70 | GRIN2B (0.38) | GRIN2BGRIN2CCYP4F2CYP4A11 | |
| SCHEMBL8484892 | 0.70 | JAK3 (0.33) | GRIN2BGRIN2CCYP4F2CYP4A11 | |
| SCHEMBL19281600 | 0.70 | CYP4F2 (0.35) | GRIN2BGRIN2CCYP4F2CYP4A11 | |
| SCHEMBL28905835 | 0.69 | GRIN2B (0.40) | GRIN2BGRIN2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2509942-A2 | BIS-ACYLATED HYDROXYLAMINE DERIVATIVES | Johns Hopkins University (US) | 2012-10-17 | — | — | EP | disclosed |
| WO-2011071947-A2 | BIS-ACYLATED HYDROXYLAMINE DERIVATIVES | JOHNS HOPKINS UNIVERSITY (US) | 2011-06-16 | — | — | WO | disclosed |