Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CA5A | P35218 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.33 |
| ▸ | TUBB | P07437 | 1/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8663517 | 0.82 | CA2 (0.54) | CA1CA2CA9CA5AKMT2A | |
| SCHEMBL11374760 | 0.80 | KDM4E (0.50) | CA1CA2CA9CA5AKMT2A | |
| SCHEMBL11334105 | 0.79 | ABL1 (0.50) | CA1CA2CA9CA5AKDM4E | |
| SCHEMBL6012073 | 0.79 | CA2 (0.40) | CA1CA2CA9CA5AKMT2A | |
| SCHEMBL6534338 | 0.79 | KDM4E (0.44) | CA1CA2CA9CA5AKMT2A | |
| SCHEMBL10396139 | 0.78 | CA1 (0.39) | CA1CA2CA9CA5AKMT2A | |
| SCHEMBL9814857 | 0.77 | GAA (0.39) | CA1CA2CA9CA5AKMT2A | |
| SCHEMBL6228820 | 0.76 | CA1 (0.59) | CA1CA2CA9CA5AKMT2A | |
| SCHEMBL9814815 | 0.75 | TDP1 (0.42) | CA1CA2CA9CA5AKMT2A | |
| SCHEMBL11340439 | 0.75 | POLB (0.45) | KMT2AKDM4ESMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5723409-A | Intermediates for the preparation of phenylsulfonylurea herbicides and plant growth regulators | HOECHST SCHERING AGREVO GMBH (DE) | 1998-03-03 | — | — | US | disclosed |
| EP-0666852-B1 | NEW PHENYLSULPHONYL UREAS, THEIR PREPARATION AND THEIR USE AS HERBICIDES AND PLANT-GROWTH REGULATORS | HOECHST SCHERING AGREVO GMBH (DE) | 1997-01-22 | — | — | EP | disclosed |
| US-5449812-A | Substituted benzenesulfonamide derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-09-12 | — | — | US | disclosed |
| EP-0666852-A1 | NEW PHENYLSULPHONYL UREAS, THEIR PREPARATION AND THEIR USE AS HERBICIDES AND PLANT-GROWTH REGULATORS. | HOECHST SCHERING AGREVO GMBH (DE) | 1995-08-16 | — | — | EP | disclosed |
| WO-1994010154-A1 | NEW PHENYLSULPHONYL UREAS, THEIR PREPARATION AND THEIR USE AS HERBICIDES AND PLANT-GROWTH REGULATORS | HOECHST SCHERING AGREVO GMBH (DE) | 1994-05-11 | — | — | WO | disclosed |