Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9814815 | 0.87 | TDP1 (0.42) | KDM4ECA1CA2CA5ACA9 | |
| SCHEMBL11374760 | 0.84 | KDM4E (0.50) | KDM4ECYP1A2CYP2C19CA1CA2 | |
| SCHEMBL11334105 | 0.83 | ABL1 (0.50) | KDM4ECYP1A2CYP2C19NR4A2CA1 | |
| SCHEMBL6012073 | 0.83 | CA2 (0.40) | KDM4ECA1CA2CA5ACA9 | |
| SCHEMBL10396139 | 0.82 | CA1 (0.39) | KDM4ECA1CA2CA5ACA9 | |
| SCHEMBL9814857 | 0.81 | GAA (0.39) | KDM4ECA1CA2CA5ACA9 | |
| SCHEMBL10870054 | 0.81 | L3MBTL1 (0.42) | MAPTSMN1; SMN2L3MBTL1MAPK1GAA | |
| SCHEMBL6228820 | 0.80 | CA1 (0.59) | KDM4ECA1CA2CA5ACA9 | |
| SCHEMBL11340439 | 0.79 | POLB (0.45) | KDM4EMAPTSMN1; SMN2TDP1ALDH1A1 | |
| SCHEMBL8663577 | 0.79 | CA1 (0.37) | KDM4ECA1CA2CA5ACA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004020401-A1 | SYNTHESIS OF SULFONAMIDE DERIVATIVES | SYNGENE INTERNATIONAL PRIVATE LIMITED (IN) | 2004-03-11 | — | — | WO | disclosed |
| US-4632693-A | POSTEMERGENCE GRASSES IN WHEAT | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1986-12-30 | — | — | US | disclosed |