SCHEMBL8663665

SCHEMBL8663665

CCOC(=O)c1ccc(-c2nc(-c3nc(-c4ccc(C(=O)OCC)cc4)c(-c4ccc(C(=O)OCC)cc4)n3-c3ccccc3Cl)[nH]c2-c2ccc(C(=O)OCC)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.52
RAF1 P04049 1/20 0.44
ALDH1A1 P00352 6/20 0.43
POLB P06746 2/20 0.43
KDM4E B2RXH2 4/20 0.43
GLA P06280 3/20 0.43
GAA P10253 3/20 0.43
HPGD P15428 3/20 0.43
KMT2A Q03164 3/20 0.43
MEN1 O00255 2/20 0.43
PARP1 P09874 1/20 0.43
SIRT2 Q8IXJ6 1/20 0.42
SIRT1 Q96EB6 1/20 0.42
SIRT3 Q9NTG7 1/20 0.42
RARA P10276 1/20 0.41
RARB P10826 1/20 0.41
RARG P13631 1/20 0.41
MAPT P10636 3/20 0.41
TP53 P04637 1/20 0.41
CYP1A2 P05177 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4632626 0.82 MAPK13 (0.45) RAF1ALDH1A1KDM4EGAAHPGD
SCHEMBL14648010 0.81 MAPK13 (0.52) RAF1GAAMAPTTP53MAPK13
SCHEMBL14991080 0.75 MGAM (0.46) RAF1ALDH1A1KDM4EGAAHPGD
SCHEMBL27944794 0.75 KDM4E (0.44) RAF1ALDH1A1POLBKDM4EGLA
SCHEMBL4652915 0.73 KDM4E (0.49) RAF1ALDH1A1KDM4EGLAGAA
SCHEMBL4652725 0.72 MGAM (0.47) RAF1ALDH1A1KDM4EGAAHPGD
SCHEMBL4651674 0.72 MAPK14 (0.51) ALOX5RAF1GAAHPGDKMT2A
SCHEMBL14991428 0.72 MGAM (0.46) RAF1ALDH1A1KDM4EGAAHPGD
SCHEMBL10385875 0.71 NOX1 (0.52) RAF1ALDH1A1KDM4EGAAKMT2A
SCHEMBL27925495 0.70 MGAM (0.47) ALOX5RAF1ALDH1A1KDM4EGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8822110-B2 Photosensitive resin composition for color filter and color filter including the same CHEIL INDUSTRIES INC. (KR) 2014-09-02 US disclosed
US-20130141810-A1 Photosensitive Resin Composition for Color Filter and Color Filter Using the Same CHEIL INDUSTRIES INC. (KR) 2013-06-06 US disclosed
US-20130143158-A1 Photosensitive Resin Composition for Color Filter and Color Filter Including the Same CHEIL INDUSTRIES INC. (KR) 2013-06-06 US disclosed
US-5792589-A ORGANIC BINDER; OPTICALLY CROSSLINKABLE COMPOUND; RADICAL-GENERATING AGENT: 2,4,5-TRIARYL IMIDAZOLE DIMER, AMINO-GROUP CONTAINING BENZOPHENONE PHOTOSENSITIZER, A THIOL COMPOUND JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1998-08-11 US disclosed
US-5607817-A DIALKYLAMINOPHENYL-SUBSTITUTED TRIAZINE SENSITIZER MITSUBISHI CHEMICAL CORPORATION (JP) 1997-03-04 US disclosed