SCHEMBL8663871

SCHEMBL8663871

C#CCCCCc1ccc([V](Cl)(Cl)c2cccc3c2Cc2ccccc2-3)c2c1-c1ccccc1C2

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
PNMT P11086 1/20 0.35
CYSLTR2 Q9NS75 1/20 0.33
CYSLTR1 Q9Y271 1/20 0.33
DRD2 P14416 1/20 0.30
DRD4 P21917 1/20 0.30
DRD3 P35462 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL8669031 0.76 PNMT (0.34) PNMTCYSLTR2CYSLTR1DRD2DRD4
Hydrochloric Acid SCHEMBL8669023 0.76 PNMT (0.34) PNMTCYSLTR2CYSLTR1
SCHEMBL8662797 0.75 DRD2 (0.43) PNMTCYSLTR2CYSLTR1DRD2DRD4
SCHEMBL8663891 0.74 CYSLTR2 (0.43) PNMTCYSLTR2CYSLTR1DRD2DRD4
SCHEMBL8663219 0.70 PNMT (0.36) PNMTCYSLTR2CYSLTR1DRD2DRD4
SCHEMBL8664573 0.68 PNMT (0.38) PNMTCYSLTR2CYSLTR1DRD2DRD4
SCHEMBL6675794 0.66 PNMT (0.68) PNMTDRD2DRD4DRD3
SCHEMBL7760618 0.66 PNMT (0.49) PNMTDRD2DRD4DRD3
SCHEMBL6676505 0.65 PNMT (0.66) PNMTDRD2DRD4DRD3
SCHEMBL6674622 0.65 PNMT (0.66) PNMTDRD2DRD4DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5744666-A Process for preparing an alkynyl fulvene group containing compound and said compound PHILLIPS PETROLEUM COMPANY (US) 1998-04-28 US disclosed
US-5728908-A Process for preparing a bridged ligand and said bridged ligand PHILLIPS PETROLEUM COMPANY (US) 1998-03-17 US disclosed
US-5631203-A Metallocene compounds and preparation thereof containing terminal alkynes PHILLIPS PETROLEUM COMPANY (US) 1997-05-20 US disclosed