Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.46 |
| ▸ | NAMPT | P43490 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | PPARA | Q07869 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.37 |
| ▸ | TCF7L2 | Q9NQB0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8670633 | 0.86 | HDAC1 (0.43) | HDAC1NAMPTMEN1KMT2AHDAC6 | |
| SCHEMBL8666826 | 0.85 | HDAC1 (0.40) | HDAC1NAMPTMEN1KMT2AHDAC6 | |
| SCHEMBL7289605 | 0.81 | HDAC1 (0.48) | HDAC1NAMPTMEN1KMT2AHDAC6 | |
| SCHEMBL7289755 | 0.75 | ROCK2 (0.45) | HDAC1NAMPTMEN1KMT2AL3MBTL1 | |
| SCHEMBL28641617 | 0.75 | NAMPT (0.53) | HDAC1NAMPTMEN1KMT2AHDAC6 | |
| SCHEMBL9221746 | 0.74 | NAMPT (0.57) | HDAC1NAMPTMEN1KMT2AHDAC6 | |
| SCHEMBL8665767 | 0.74 | HDAC1 (0.45) | HDAC1NAMPTMEN1KMT2AHDAC6 | |
| SCHEMBL7289218 | 0.73 | HDAC1 (0.56) | HDAC1NAMPTMEN1KMT2AHDAC6 | |
| SCHEMBL4888860 | 0.72 | NAMPT (0.61) | HDAC1NAMPTMEN1KMT2AHDAC6 | |
| SCHEMBL7282483 | 0.71 | NAMPT (0.43) | HDAC1NAMPTMEN1KMT2AHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5760057-A | ANTICOAGULANTS | ZENECA LIMITED (GB) | 1998-06-02 | — | — | US | disclosed |