SCHEMBL866395

SCHEMBL866395

Cc1cc(O)c(C(C)(C)C)cc1C(C)(C)c1cc(C(C)(C)C)c(O)cc1C

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 7/20 0.61
ALDH1A1 P00352 7/20 0.61
SMN1; SMN2 Q16637 4/20 0.61
CYP1A2 P05177 3/20 0.61
MAPT P10636 3/20 0.61
KDM4E B2RXH2 2/20 0.61
ATP2A2 P16615 1/20 0.61
ATP2A3 Q93084 1/20 0.61
HIF1A Q16665 4/20 0.59
TP53 P04637 3/20 0.59
CYP3A4 P08684 3/20 0.59
TSHR P16473 2/20 0.59
TDP1 Q9NUW8 2/20 0.59
MAPK1 P28482 2/20 0.59
CYP2C9 P11712 6/20 0.49
CYP2C19 P33261 5/20 0.49
CYP2D6 P10635 3/20 0.49
LMNA P02545 2/20 0.45
HPGD P15428 2/20 0.45
HSD17B10 Q99714 3/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30747043 1.00 ALOX15 (0.61) ALOX15ALDH1A1SMN1; SMN2CYP1A2MAPT
SCHEMBL824520 0.91 ALOX15 (0.67) ALOX15ALDH1A1SMN1; SMN2CYP1A2MAPT
SCHEMBL29395805 0.91 ALOX15 (0.67) ALOX15ALDH1A1SMN1; SMN2CYP1A2MAPT
SCHEMBL27515308 0.88 ALOX15 (0.64) ALOX15ALDH1A1SMN1; SMN2CYP1A2MAPT
SCHEMBL7018654 0.87 ALOX15 (0.47) ALOX15ALDH1A1SMN1; SMN2CYP1A2MAPT
SCHEMBL14716742 0.84 ALDH1A1 (0.58) ALOX15ALDH1A1SMN1; SMN2CYP1A2MAPT
SCHEMBL29872633 0.83 ALOX15 (0.70) ALOX15ALDH1A1SMN1; SMN2CYP1A2MAPT
SCHEMBL395984 0.83 ALOX15 (0.70) ALOX15ALDH1A1SMN1; SMN2CYP1A2MAPT
SCHEMBL780049 0.83 ESR1 (0.50) ALOX15ALDH1A1SMN1; SMN2CYP1A2MAPT
SCHEMBL5212796 0.83 ALDH1A1 (0.56) ALOX15ALDH1A1SMN1; SMN2CYP1A2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 185 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090163692-A1 AROMATIC POLYETHERS GENERAL ELECTRIC COMPANY (US) 2009-06-25 US claimed
EP-1763560-A1 POLYARYLATE COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 2007-03-21 EP claimed
US-7109274-B2 Polyarylate compositions GENERAL ELECTRIC COMPANY (US) 2006-09-19 US claimed
WO-2006012161-A1 POLYARYLATE COMPOSITIONS GENERAL ELECTRIC COMPANY (US) 2006-02-02 WO claimed
US-20060004152-A1 Polyarylate compositions GENERAL ELECTRIC COMPANY 2006-01-05 US claimed
EP-1805130-B1 METHOD FOR THE PREPARATION OF ALIPHATIC CHLOROFORMATES SABIC INNOVATIVE PLASTICS IP (NL) 2015-01-28 EP disclosed
US-8877341-B2 Polycarbonate resin and optical film using the same MITSUBISHI GAS CHEMICAL COMPANY, INC (JP) 2014-11-04 US disclosed
US-20130245223-A1 HIGH HEAT POLYETHERSULFONE COMPOSITIONS SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2013-09-19 US disclosed
EP-1945696-B1 METHOD OF IMPROVING ABRASION RESISTANCE OF PLASTIC ARTICLE USING FUNCTIONALIZED POLYMERS AND ARTICLE PRODUCED THEREBY SABIC INNOVATIVE PLASTICS IP (NL) 2013-07-31 EP disclosed
US-8343899-B2 Bearing lubricating oil and bearing SATO SPECIAL OIL CO., LTD. (JP) 2013-01-01 US disclosed
US-20120076449-A1 BEARING LUBRICATING OIL AND BEARING SATO SPECIAL OIL CO., LTD. (JP) 2012-03-29 US disclosed
EP-1971631-B1 THERMALLY STABLE POLYCARBONATES, THERMOPLASTIC COMPOSITIONS THEREOF, AND ARTICLES FORMED THEREFROM SABIC INNOVATIVE PLASTICS IP (NL) 2011-09-21 EP disclosed
US-4522735-A Polyphosphoramidite oligomers and stabilizer compositions thereof THE B. F. GOODRICH COMPANY (US) 1985-06-11 US disclosed
US-4507671-A DIMETHYL 4-HYDROXY-PHTHALATE AS COLOR DEVELOPER, AND A DYE PRECURS MITSUBISHI PAPER MILLS, LTD. (JP) 1985-03-26 US disclosed
US-4472548-A HYDROXYPHENYLALKYL ISOCYANURATE, STABILIZERS THE B. F. GOODRICH COMPANY (US) 1984-09-18 US disclosed
US-4284699-A Polyester binder component in multilayer photoconductive element EASTMAN KODAK COMPANY (US) 1981-08-18 US disclosed
US-4173472-A Polyester interlayer and binder component in multilayer photoconductive element EASTMAN KODAK COMPANY (US) 1979-11-06 US disclosed
US-4052325-A LIQUID ELECTROGRAPHIC DEVELOPER COMPOSITION CONTAINING REDISPERSIBLE POLYESTER TONER AND PROCESS EASTMAN KODAK COMPANY (US) 1977-10-04 US disclosed
US-4013618-A NITROGEN-CONTAINING STABILIZER TOYOBO CO., LTD. (JA) 1977-03-22 US disclosed
US-3957905-A HALOGENATED BISPHENYL COMPOUND, ANTIMONY COMPOUND TOYO BOSEKI KABUSHIKI KAISHA (JA) 1976-05-18 US disclosed