Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8658182 | 0.91 | KDM4E (0.32) | MAP3K14 | |
| SCHEMBL8663440 | 0.88 | MAP3K14 (0.30) | MAP3K14 | |
| SCHEMBL8661593 | 0.84 | — | — | |
| SCHEMBL8661859 | 0.84 | PTGS2 (0.31) | — | |
| SCHEMBL8662214 | 0.82 | — | — | |
| SCHEMBL8661283 | 0.82 | — | — | |
| SCHEMBL8664156 | 0.81 | NPC1 (0.31) | — | |
| SCHEMBL8661991 | 0.81 | — | — | |
| SCHEMBL8663351 | 0.80 | KMT2A (0.31) | — | |
| SCHEMBL7651580 | 0.80 | AKR1B1 (0.32) | MAP3K14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750693-A | THIOCHROMANYL OR CHROMANYL COMPOUNDS AS ANTICARCINOGINIC AGENTS, SKIN DISORDERS AND ATHEROSCLEROSIS | ALLERGAN (US) | 1998-05-12 | — | — | US | disclosed |