Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.47 |
| ▸ | PRKACA | P17612 | 4/20 | 0.45 |
| ▸ | AHCY | P23526 | 2/20 | 0.43 |
| ▸ | DOT1L | Q8TEK3 | 4/20 | 0.42 |
| ▸ | HSP90B1 | P14625 | 2/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1094627 | 0.66 | ADORA3 (0.61) | ADORA3ADORA2APRKACADOT1LADORA2B | |
| SCHEMBL2550745 | 0.65 | ADORA3 (0.69) | ADORA3ADORA2AADORA1 | |
| Water SCHEMBL1094113 | 0.65 | ADORA3 (0.68) | ADORA3ADORA2AADORA1 | |
| SCHEMBL25046610 | 0.64 | PRKACA (0.77) | ADORA3ADORA2APRKACAAHCYHSP90B1 | |
| SCHEMBL30941201 | 0.64 | PRKACA (0.77) | ADORA3ADORA2APRKACAAHCYHSP90B1 | |
| SCHEMBL29707951 | 0.63 | ADORA1 (0.63) | ADORA3ADORA2APRKACADOT1LADORA2B | |
| SCHEMBL15993927 | 0.63 | ADORA1 (0.63) | ADORA3ADORA2APRKACADOT1LADORA2B | |
| SCHEMBL25269461 | 0.63 | ADORA1 (0.63) | ADORA3ADORA2APRKACADOT1LADORA2B | |
| SCHEMBL29360147 | 0.63 | PRKACA (1.00) | ADORA3ADORA2APRKACAHSP90B1 | |
| SCHEMBL9024927 | 0.62 | PRMT5 (0.58) | ADORA3ADORA2AAHCYDOT1LHSP90B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773423-A | XANTHINE RIBOSIDES | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1998-06-30 | — | — | US | disclosed |