Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 5/20 | 0.58 |
| ▸ | P2RY1 | P47900 | 4/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | P2RY2 | P41231 | 3/20 | 0.58 |
| ▸ | SRC | P12931 | 2/20 | 0.58 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.58 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.58 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.58 |
| ▸ | LDHA | P00338 | 1/20 | 0.58 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.58 |
| ▸ | FBP1 | P09467 | 1/20 | 0.58 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.58 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.58 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.58 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.58 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.58 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.58 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7860970 | 0.91 | ADORA1 (0.57) | ADORA1P2RY1SMN1; SMN2P2RY2SRC | |
| SCHEMBL5356782 | 0.88 | ADORA3 (0.65) | ADORA1P2RY1SMN1; SMN2P2RY2SRC | |
| SCHEMBL13268725 | 0.87 | ADORA1 (0.60) | ADORA1P2RY1SMN1; SMN2P2RY2SRC | |
| SCHEMBL62486 | 0.87 | ADORA1 (0.65) | ADORA1P2RY1SMN1; SMN2P2RY2SRC | |
| SCHEMBL932846 | 0.87 | ADORA1 (0.65) | ADORA1P2RY1SMN1; SMN2P2RY2SRC | |
| SCHEMBL13269066 | 0.85 | ADORA1 (0.60) | ADORA1P2RY1SMN1; SMN2P2RY2SRC | |
| SCHEMBL13834596 | 0.85 | ADORA1 (0.60) | ADORA1P2RY1SMN1; SMN2P2RY2SRC | |
| SCHEMBL13269154 | 0.85 | PDE2A (0.66) | ADORA1P2RY1SMN1; SMN2P2RY2SRC | |
| SCHEMBL4541368 | 0.85 | ADORA1 (0.64) | ADORA1P2RY1SMN1; SMN2P2RY2SRC | |
| SCHEMBL13269088 | 0.85 | ADORA1 (0.62) | ADORA1P2RY1SMN1; SMN2P2RY2SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773423-A | XANTHINE RIBOSIDES | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1998-06-30 | — | — | US | disclosed |
| EP-0689405-A4 | METHODS FOR PROTECTING TISSUES AND ORGANS FROM ISCHEMIC DAMAGE | GENSIA INC (US) | 1996-09-11 | — | — | EP | disclosed |
| EP-0689405-A1 | METHODS FOR PROTECTING TISSUES AND ORGANS FROM ISCHEMIC DAMAGE | GENSIA, INC. (US) | 1996-01-03 | — | — | EP | disclosed |
| WO-1994021195-A1 | METHODS FOR PROTECTING TISSUES AND ORGANS FROM ISCHEMIC DAMAGE | GENSIA, INC. (US) | 1994-09-29 | — | — | WO | disclosed |