SCHEMBL8664400

SCHEMBL8664400

O=C(Cc1ccc(OCc2nc3cc(Cl)ccc3s2)cc1)NCl

nearest known ligand 0.53

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 10/20 0.53
EPHX2 P34913 10/20 0.53
HDAC6 Q9UBN7 1/20 0.48
ALDH1A1 P00352 2/20 0.46
MAPT P10636 2/20 0.46
MEN1 O00255 1/20 0.46
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
KMT2A Q03164 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
CSNK1D P48730 2/20 0.45
LOXL2 Q9Y4K0 1/20 0.45
PTGDR2 Q9Y5Y4 1/20 0.43
KDM4E B2RXH2 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
ALOX5AP P20292 1/20 0.43
PTGER4 P35408 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8663798 0.88 CSNK1D (0.49) ALOX5EPHX2ALDH1A1MAPTMEN1
SCHEMBL8663180 0.88 ALDH1A1 (0.47) ALOX5EPHX2ALDH1A1MAPTMEN1
SCHEMBL8663322 0.88 PTGER4 (0.54) ALOX5EPHX2HDAC6ALDH1A1MAPT
SCHEMBL8666834 0.85 CSNK1D (0.48) ALOX5EPHX2ALDH1A1MAPTMEN1
SCHEMBL8665633 0.85 NPC1 (0.44) ALOX5EPHX2ALDH1A1MAPTMEN1
SCHEMBL8665133 0.82 NPC1 (0.51) ALOX5EPHX2ALDH1A1MAPTMEN1
SCHEMBL8666293 0.82 CSNK1D (0.60) ALDH1A1MAPTCSNK1DKDM4E
SCHEMBL8664253 0.82 SMN1; SMN2 (0.47) ALOX5EPHX2ALDH1A1MAPTMEN1
SCHEMBL7541432 0.79 EPHX2 (0.65) ALOX5EPHX2HDAC6ALDH1A1MAPT
SCHEMBL7551712 0.78 EPHX2 (0.64) ALOX5EPHX2HDAC6ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5736487-A HERBICIDES SANKYO COMPANY, LIMITED (JP) 1998-04-07 US disclosed