SCHEMBL8666293

SCHEMBL8666293

COc1ccc2nc(COc3ccc(CC(=O)NCl)cc3)sc2c1

nearest known ligand 0.60

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CSNK1D P48730 9/20 0.60
WNT3A P56704 7/20 0.53
CYP3A4 P08684 1/20 0.53
CASP2 P42575 1/20 0.51
KDM4E B2RXH2 1/20 0.51
ALDH1A1 P00352 1/20 0.51
GAA P10253 1/20 0.51
MAPT P10636 1/20 0.51
SCD O00767 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8663798 0.92 CSNK1D (0.49) CSNK1DWNT3ACYP3A4ALDH1A1MAPT
SCHEMBL8664253 0.89 SMN1; SMN2 (0.47) CSNK1DWNT3AALDH1A1MAPT
SCHEMBL8665353 0.88 CSNK1D (0.59) CSNK1DWNT3ACYP3A4KDM4EALDH1A1
SCHEMBL8665133 0.87 NPC1 (0.51) CSNK1DWNT3AKDM4EALDH1A1MAPT
SCHEMBL8665633 0.84 NPC1 (0.44) CSNK1DKDM4EALDH1A1MAPT
SCHEMBL8663180 0.83 ALDH1A1 (0.47) KDM4EALDH1A1MAPT
SCHEMBL8664400 0.82 ALOX5 (0.53) CSNK1DKDM4EALDH1A1MAPT
SCHEMBL8663322 0.81 PTGER4 (0.54) ALDH1A1MAPT
SCHEMBL8664162 0.80 NPC1 (0.51) CSNK1DWNT3ACYP3A4ALDH1A1MAPT
SCHEMBL7542768 0.79 MAPT (0.64) CYP3A4KDM4EALDH1A1GAAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5736487-A HERBICIDES SANKYO COMPANY, LIMITED (JP) 1998-04-07 US disclosed