⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL997169 | 1.00 | — | — | |
| SCHEMBL8385562 | 1.00 | — | — | |
| SCHEMBL13091634 | 0.83 | MTNR1A (0.53) | — | |
| SCHEMBL23083767 | 0.82 | ACACB (0.43) | — | |
| SCHEMBL12707415 | 0.82 | MEN1 (0.46) | — | |
| SCHEMBL23083775 | 0.82 | ACACB (0.43) | — | |
| SCHEMBL13645986 | 0.82 | ACACB (0.43) | — | |
| SCHEMBL6422972 | 0.81 | — | — | |
| SCHEMBL15744585 | 0.81 | ALDH1A1 (0.46) | — | |
| SCHEMBL3132686 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230257380-A1 | TROPOMYOSIN RECEPTOR KINASE (TRK) DEGRADATION COMPOUNDS AND METHODS OF USE | CULLGEN (SHANGHAI), INC. (CN) | 2023-08-17 | — | — | US | disclosed |
| EP-0877815-A1 | METHOD OF PRODUCING OPTICALLY ACTIVE AMINES | BAYER AG (DE) | 1998-11-18 | — | — | EP | disclosed |
| WO-1997028271-A1 | METHOD OF PRODUCING OPTICALLY ACTIVE AMINES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-08-07 | — | — | WO | disclosed |